You are looking at the quantitative interactomic profile of the site PDZ_2 of PREX2


UniProt ID: Q70Z35
Molecule ID: PREX2 (Link to all interactions of this molecule.)
Alternative name(s): DEPDC2


The selection have 1 unique variants
non-modified profile

The selection have 1 unique fragments
665-775 fragment

The selection have 1 unique sites
PDZ_2 sites

The current selection is unique





You see an affinity binding profile calculated for site-specific interactions, where affinities measured using the same site of the same molecules are combined. To access affinities of the entire molecule or other functional fragments or sites, go back to the molecular interaction page.


Partners Experiment
IDUniProtSiteModificationCore SequencepKd
Site-specific affinities
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
FZD7O75084PBMSHSSKGETAV4.301
FRMPD4Q14CM0PBMRLPKIKETTV4.251
ARHGEF16Q5VV41PBMMERLRVETDV4.171
HPV18-E6P06463PBMRLQRRRETQV4.001
NET1Q7Z628PBMSGGKRKETLV3.791
HPV35-E6P27228PBMSKPTRRETEV3.621
HPV16-E6P03126PBMSSRTRRETQLnot detectable6
WNV-NS5Q9Q6P4PBMDTTLVEDTVLnot detectable4
HBV-HbcP03146PBMRRSQSRESQCnot detectable2
MERS-EK9N5R3PBMKPPLPPDEWVnot detectable2
PTENP60484PBMEDQHTQITKVnot detectable2
SARS-CoV2-EP0DTC4PBMNSSRVPDLLVnot detectable2
SARS-Cov-EP59637PBMSSEGVPDLLVnot detectable2
SARS-Cov2-3aP0DTC3PBMEPTTTTSVPLnot detectable2
SARS-Cov2-NP0DTC9PBMSMSSADSTQAnot detectable2
ABCC4O15439PBMSTLTIFETALnot detectable1
ASIC3Q9UHC3PBMHRTCYLVTQLnot detectable1
ATP2B4P23634PBMSSLQSLETSVnot detectable1
CBPQ92793PBMDTLEKFVEGLnot detectable1
CYSLTR2Q9NS75PBMSVWLRKETRVnot detectable1
DGKKQ5KSL6PBMDPLTPSRSQLnot detectable1
DGKZQ13574PBMIQREDQETAVnot detectable1
DOCK4Q8N1I0PBMRPLPRKVSQLnot detectable1
GRASPQ7Z6J2PBMRSLEEEESQLnot detectable1
HPV16-E6P03126PBM(TPO)156SSRTRRETQLnot detectable1
HPV30-E6P36809PBMRHTTSTETAVnot detectable1
HPV33-E6P06427PBMSRSRRRETALnot detectable1
HPV51-E6P26554PBMRTRQRNETQVnot detectable1
HPV59-E6Q81964PBMQRQARSETLVnot detectable1
HPV67-E6A4U7F2PBMSRPQRTQTQVnot detectable1
HPV73-E6Q82005PBMSGSRPSATVVnot detectable1
HPV82-E6Q9IR59PBMPPRQRSETQVnot detectable1
HTLV1-TAX1P03409PBMSEKHFRETEVnot detectable1
KCNA5P22460PBMCLDTSRETDLnot detectable1
KIR3DL3Q8N743PBMPKTPPTDTSVnot detectable1
MAP2K2P36507PBMQPGTPTRTAVnot detectable1
PBKQ96KB5PBMHIVEALETDVnot detectable1
PTENP60484PBM(ALY)402EDQHTQITKVnot detectable1
RALBP1Q15311PBMPSRDRKETSInot detectable1
RASSF6Q6ZTQ3PBMKLVIKTETTVnot detectable1
RPS6KA1Q15418PBM(SEP)732RVRKLPSTTLnot detectable1
SLC15A5A6NIM6PBMSSIDLWETALnot detectable1
SLCO1C1Q9NYB5PBMNYWPGKETQLnot detectable1
TJP2Q9UDY2PBMQSARYRDTELnot detectable1





The database contains 6 motifs with quantifiable (site-specific) affinities to the selected protein.
Out of these, 6 affinities are above the threshold (3.5 pKd).
Interactions above the threshold are used for LOGO calculation.

Frequency LOGO

Affinity-weighted frequency LOGO

Modify the parameters of LOGO calculation:


Threshold: pKd    

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