ProfAff

You are looking at the quantitative interactomic profile of the (TPO)458 modified site 14-3-3_pThr458 of SPIR1

UniProt ID: Q08AE8
Molecule ID: SPIR1 (Link to all interactions of this molecule.)
Alternative name(s): SPIRE1 KIAA1135 SPIR1
Sequence of fragment: LLRAPTLAEL

The selection have 1 unique variants
(TPO)458 modified profile

You accessed the interactomic profile with a defined modification. See all possible variants of the same selection.

The selection have 1 unique fragments
453-462 fragment

The selection have 1 unique sites
14-3-3_pThr458 sites

The current selection is unique

You see an affinity binding profile calculated for site-specific interactions, where affinities measured using the same site of the same molecules are combined. To access affinities of the entire molecule or other functional fragments or sites, go back to the molecular interaction page.

Selection	Partners				Experiment
Modification	ID	UniProt	Site	Modification	pK_{d Site-specific affinities are averaged on this page.}	St.dev Standard deviation is calculated using affinities obtained from independent experiment series. * indicates that affinity was not detectable in all experiments	n	QI Quality indicator n > 1 and St.dev < 0.5 pKd n > 1 and St.dev > 0.5 pKd or only detectable in a subset of experiment series n > 1, but originating from a single experiment series n = 1
(TPO)458	YWHAB	P31946	14-3-3		not detectable		9
(TPO)458	YWHAG	P61981	14-3-3		not detectable		5
(TPO)458	YWHAH	Q04917	14-3-3		not detectable		5
(TPO)458	YWHAZ	P63104	14-3-3		not detectable		5
(TPO)458	SFN	P31947	14-3-3		not detectable		4
(TPO)458	SFN	P31947	14-3-3	100_uM_FCA	not detectable		4
(TPO)458	YWHAE	P62258	14-3-3		not detectable		4
(TPO)458	YWHAG	P61981	14-3-3	100_uM_FCA	not detectable		4

Unfortunately, the current database do not contain any motif with quantified affinity for this selected protein.

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