ProfAff

You are looking at the quantitative interactomic profile of the site 14-3-3_pSer718 of USP8

UniProt ID: P40818
Molecule ID: USP8 (Link to all interactions of this molecule.)
Alternative name(s): USP8 KIAA0055 UBPY
Sequence of fragment: LKRSYSSPDI

The selection have 1 unique variants
(SEP)718 modified profile

The selection have 2 unique fragments
712-724 fragment
713-722 fragment

The selection have 1 unique sites
14-3-3_pSer718 sites

The current selection is a unique site

You see an affinity binding profile calculated for site-specific interactions, where affinities measured using the same site of the same molecules are combined. To access affinities of the entire molecule or other functional fragments or sites, go back to the molecular interaction page.

Selection	Partners				Experiment
Modification	ID	UniProt	Site	Modification	pK_{d Site-specific affinities are averaged on this page.}	St.dev Standard deviation is calculated using affinities obtained from independent experiment series. * indicates that affinity was not detectable in all experiments	n	QI Quality indicator n > 1 and St.dev < 0.5 pKd n > 1 and St.dev > 0.5 pKd or only detectable in a subset of experiment series n > 1, but originating from a single experiment series n = 1
(SEP)718	YWHAG	P61981	14-3-3	100_uM_FCA	5.00	0.00	2
(SEP)718	YWHAG	P61981	14-3-3		4.97	0.61	15
(SEP)718	YWHAH	Q04917	14-3-3		4.91	0.51	10
(SEP)718	YWHAB	P31946	14-3-3		4.85	0.41	15
(SEP)718	YWHAZ	P63104	14-3-3		4.84	0.45	10
(SEP)718	YWHAQ	P27348	14-3-3		4.74	0.43	10
(SEP)718	SFN	P31947	14-3-3	100_uM_FCA	4.72		4
(SEP)718	YWHAE	P62258	14-3-3		4.50	0.24	18
(SEP)718	SFN	P31947	14-3-3		4.46	0.21	18

Unfortunately, the current database do not contain any motif with quantified affinity for this selected protein.

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