ProfAff

You are looking at the quantitative interactomic profile of the fragment 2834-2843 of APC

UniProt ID: P25054
Molecule ID: APC (Link to all interactions of this molecule.)
Alternative name(s): DP2.5
Sequence of fragment: HSGSYLVTSV

The selection have 1 unique variants
non-modified profile

The selection have 1 unique fragments
2834-2843 fragment

The selection have 1 unique sites
PBM sites

The current selection is unique

You see an affinity binding profile calculated for fragment-specific interactions, where affinities measured using the same fragments of the same molecules are combined. To access affinities of the entire molecule or other functional sites or fragments, go back to the molecular interaction page.

Partners				Experiment
ID	UniProt	Fragment	Site	pK_d Affinities measured between specific fragments are averaged on this page.	St.dev Standard deviation is calculated using affinities obtained from independent experiment series. * indicates that affinity was not detectable in all experiments	n	QI Quality indicator n > 1 and St.dev < 0.5 pKd n > 1 and St.dev > 0.5 pKd or only detectable in a subset of experiment series n > 1, but originating from a single experiment series n = 1
SNX27	Q96L92	40-141	PDZ	5.58	0.09	3
TX1BP3	O14907	7-124	PDZ	5.51	0.03	2
DLG1	Q12959	314-412	PDZ_2	5.17	0.04	2
MAST2	Q6P0Q8	1102-1193	PDZ	5.16	0.07	3
SCRIB	Q14160	718-814	PDZ_1	5.10	0.09	3
ARHGEF12	Q9NZN5	67-151	PDZ	5.09	0.07	2
PDZD7	Q9H5P4	858-953	PDZ_3	5.07	0.04	2
RHPN1	Q8TCX5	504-602	PDZ	5.07	0.09	2
DLG4	P78352	155-249	PDZ_2	5.05	0.07	2
GRASP	Q7Z6J2	96-193	PDZ	5.01	0.05	2
DLG3	Q92796	221-314	PDZ_2	5.00	0.07	2
DLG1	Q12959	457-570	PDZ_3	4.94	0.06	2
DLG2	Q15700	189-283	PDZ_2	4.93	0.18	2
LAP2	Q96RT1	1314-1412	PDZ	4.89	0.02	3
SYNJ2BP	P57105	6-103	PDZ	4.88	0.09	3
Inadl	Q8NI35	1425-1530	PDZ_8	4.86	0.02	2
DLG2	Q15700	418-513	PDZ_3	4.79	0.12	2
MAGI2	Q86UL8	1141-1229	PDZ_6	4.76	0.09	2
ARHGEF11	O15085	41-126	PDZ	4.73	0.14	2
DLG3	Q92796	381-476	PDZ_3	4.70	0.01	2
PTPN3	P26045	505-597	PDZ	4.67	0.03	2
LNX2	Q8N448	334-426	PDZ_2	4.63	0.07	2
MAGI2	Q86UL8	915-1017	PDZ_5	4.62	0.01	2
MAGI3	Q5TCQ9	398-503	PDZ_2	4.59	0.06	2
FRMPD2	Q68DX3	944-1038	PDZ_2	4.57	0.04	2
HTRA4	P83105	368-476	PDZ	4.57	0.06	2
SCRIB	Q14160	999-1093	PDZ_3	4.57	0.12	2
DLG1	Q12959	221-314	PDZ_1	4.55	0.05	2
DLG4	P78352	306-403	PDZ_3	4.51	0.01	3
GRID2IP	A4D2P6	272-370	PDZ_2	4.49	0.08	2
DLG4	P78352	62-152	PDZ_1	4.48	0.10	2
MAST1	Q9Y2H9	965-1056	PDZ	4.44	0.22	2
PDZD2	O15018	326-424	PDZ_2	4.44	0.02	2
GORASP2	Q9H8Y8	1-208	PDZ	4.38	0.02	2
MAGI2	Q86UL8	600-682	PDZ_3	4.37	0.07	2
LNX1	Q8TBB1	261-371	PDZ_1	4.35	0.11	2
SCRIB	Q14160	858-949	PDZ_2	4.31	0.02	2
GOPC	Q9HD26	278-373	PDZ	4.29	0.01	2
MAGI2	Q86UL8	410-522	PDZ_2	4.25	0.09	3
MAGI2	Q86UL8	772-865	PDZ_4	4.24	0.07	2
RADIL	Q96JH8	973-1075	PDZ	4.24	0.01	2
SNTG1	Q9NSN8	54-143	PDZ	4.23	0.00	2
PICK1	Q9NRD5	18-110	PDZ	4.22	*	2, detectable in 1
HTRA1	Q92743	365-480	PDZ	4.21	0.01	3
LRRC7	Q96NW7	1445-1536	PDZ	4.20	0.06	2
SNTB1	Q13884	107-196	PDZ	4.18	0.13	2
MAGI1	Q96QZ7	456-580	PDZ_2	4.11	0.06	2
SHANK1	Q9Y566	655-761	PDZ	4.10	0.00	2
MPDZ	O75970	1624-1716	PDZ_10	4.07	0.01	2
APBA1	Q02410	743-822	PDZ_2	4.03	0.00	2
DFNB31	Q9P202	136-226	PDZ_1	3.97	0.04	2
PDZRN4	Q6ZMN7	214-318	PDZ_1	3.93	*	2, detectable in 1
NHERF4	Q86UT5	106-208	PDZ_1	3.90	*	2, detectable in 1
ARHGAP21	Q5T5U3	47-159	PDZ	3.89	*	2, detectable in 1
Inadl	Q8NI35	1058-1167	PDZ_6	3.88	0.07	2
DLG3	Q92796	124-219	PDZ_1	3.87	0.04	2
Inadl	Q8NI35	1673-1763	PDZ_10	3.81	0.17	2
LNX1	Q8TBB1	371-470	PDZ_2	3.81	0.02	2
TJP2	Q9UDY2	24-128	PDZ_1	3.78	*	2, detectable in 1
SNTG2	Q9NY99	70-159	PDZ	3.77	0.18	2
SNTA1	Q13424	84-171	PDZ	3.76	0.12	2
HTRA2	O43464	355-458	PDZ	3.74	*	2, detectable in 1
LIN7C	Q9NUP9	85-176	PDZ	3.72	*	2, detectable in 1
NHERF2	Q15599	142-238	PDZ_2	3.72	*	2, detectable in 1
IL16	Q14005	210-306	PDZ_1	3.70	0.12	2
PDZRN3	Q9UPQ7	245-339	PDZ_1	3.70	*	2, detectable in 1
NOS1	P29475	9-101	PDZ	3.68	*	2, detectable in 1
DFNB31	Q9P202	813-904	PDZ_3	3.67	*	2, detectable in 1
GORASP1	Q9BQQ3	1-208	PDZ	3.66	0.05	2
Inadl	Q8NI35	359-469	PDZ_3	3.64	*	2, detectable in 1
MPDZ	O75970	1858-1949	PDZ_12	3.63	*	2, detectable in 1
HTRA3	P83110	353-453	PDZ	3.57	*	2, detectable in 1
Inadl	Q8NI35	1530-1615	PDZ_9	3.57	*	2, detectable in 1
PARD3B	Q8TEW8	184-299	PDZ_1	3.56	*	2, detectable in 1
APBA3	O96018	390-479	PDZ_1	3.53	*	2, detectable in 1
NHERF4	Q86UT5	220-307	PDZ_2	3.53	*	2, detectable in 1
TJP1	Q07157	184-264	PDZ_2	3.53	*	2, detectable in 1
GRIP2	Q9C0E4	238-339	PDZ_3	3.52	*	2, detectable in 1
LIN7A	O14910	100-191	PDZ	3.51	*	2, detectable in 1
GRIP2	Q9C0E4	934-1023	PDZ_7	3.50	*	2, detectable in 1
NHERF3	Q5T2W1	375-459	PDZ_4	3.48	*	2, detectable in 1
FRMPD4	Q14CM0	67-160	PDZ	not detectable		3
APBA1	Q02410	655-741	PDZ_1	not detectable		2
APBA2	Q99767	565-653	PDZ_1	not detectable		2
APBA2	Q99767	655-735	PDZ_2	not detectable		2
CARD11	Q9BXL7	660-756	PDZ	not detectable		2
CASK	O14936	487-570	PDZ	not detectable		2
DFNB31	Q9P202	263-379	PDZ_2	not detectable		2
DLG5	Q8TDM6	616-713	PDZ_1	not detectable		2
DVL3	Q92997	244-343	PDZ	not detectable		2
FRMPD1	Q5SYB0	53-142	PDZ	not detectable		2
FRMPD2	Q68DX3	1073-1166	PDZ_3	not detectable		2
FRMPD2	Q68DX3	770-861	PDZ_1	not detectable		2
FRMPD3	Q5JV73	45-133	PDZ	not detectable		2
GIPC2	Q8TF65	112-203	PDZ	not detectable		2
GRID2IP	A4D2P6	1-87	PDZ_1	not detectable		2
GRIP1	Q9Y3R0	145-239	PDZ_2	not detectable		2
GRIP1	Q9Y3R0	242-344	PDZ_3	not detectable		2
GRIP1	Q9Y3R0	464-567	PDZ_4	not detectable		2
GRIP1	Q9Y3R0	563-659	PDZ_5	not detectable		2
GRIP1	Q9Y3R0	996-1086	PDZ_7	not detectable		2
GRIP2	Q9C0E4	446-548	PDZ_4	not detectable		2
GRIP2	Q9C0E4	544-642	PDZ_5	not detectable		2
GRIP2	Q9C0E4	649-740	PDZ_6	not detectable		2
IL16	Q14005	1106-1201	PDZ_3	not detectable		2
IL16	Q14005	1203-1332	PDZ_4	not detectable		2
InaDl	Q8NI35	113-229	PDZ_1	not detectable		2
InaDl	Q8NI35	238-335	PDZ_2	not detectable		2
InaDl	Q8NI35	547-651	PDZ_4	not detectable		2
InaDl	Q8NI35	673-780	PDZ_5	not detectable		2
LDB3	O75112	1-85	PDZ	not detectable		2
LIMK2	P53671	143-248	PDZ	not detectable		2
LIN7B	Q9HAP6	85-176	PDZ	not detectable		2
LNX1	Q8TBB1	500-596	PDZ_3	not detectable		2
LNX2	Q8N448	459-560	PDZ_3	not detectable		2
MAGI1	Q96QZ7	1-106	PDZ_1	not detectable		2
MPDZ	O75970	688-793	PDZ_5	not detectable		2
MPP2	Q14168	160-245	PDZ	not detectable		2
MPP6	Q9NZW5	126-208	PDZ	not detectable		2
MPP7	Q5T2T1	120-224	PDZ	not detectable		2
NHERF3	Q5T2W1	2-107	PDZ_1	not detectable		2
NHERF3	Q5T2W1	238-329	PDZ_3	not detectable		2
NHERF4	Q86UT5	464-550	PDZ_4	not detectable		2
PARD3	Q8TEW0	582-685	PDZ_3	not detectable		2
PCLO	Q9Y6V0	4484-4598	PDZ	not detectable		2
PDLIM1	O00151	1-87	PDZ	not detectable		2
PTPN13	Q12923	1085-1188	PDZ_1	not detectable		2
RAPGEF6	Q8TEU7	525-611	PDZ	not detectable		2
SIPA1L2	Q9P2F8	943-1027	PDZ	not detectable		2
TIAM2	Q8IVF5	878-980	PDZ	not detectable		2
TJP1	Q07157	415-516	PDZ_3	not detectable		2
TJP3	O95049	373-482	PDZ_3	not detectable		2
AHNAK	Q9BSE5	2-99	PDZ	not detectable		1
AHNAK1	Q09666	2-99	PDZ	not detectable		1

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