You are looking at the quantitative interactomic profile of the molecule of SHANK1


UniProt ID: Q9Y566
Molecule ID: SHANK1 (Link to all interactions of this molecule.)


The selection have 1 unique variants
non-modified profile

The selection have 1 unique fragments
655-761 fragment

The selection have 1 unique sites
PDZ sites

The current selection is unique





You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


Partners Experiment
IDUniProtModificationpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
SLC5A12Q1EHB45.811
SLC22A11Q9NSA05.681
SLCO1A2P467215.621
TRPC5Q9UL625.611
SLC15A5A6NIM65.570.324
DLGAP4Q9Y2H05.541
ARHGAP17Q68EM75.531
YAP1P469375.401
SLC34A1Q064955.391
SLC22A9Q8IVM85.361
AKAP10O435725.331
WWTR1Q9GZV55.291
ABCC4O154395.280.124
CACNA1DQ016685.281
USH1CQ9Y6N95.251
ASIC3Q9UHC35.240.233
OTULINQ96BN85.220.113
GNG4P501505.211
UNC93AQ86WB75.211
GRASPQ7Z6J25.200.092
RPS6KA3P518125.161
CFTRP135695.110.042
PTPN18Q999525.051
TBC1D10AQ9BXI64.991
SLC22A12Q96S374.961
PODXLO005924.951
SLC17A1Q149164.911
NLGN4XQ8N0W44.881
PTH1RQ034314.851
SLC15A2Q163484.851
CAPN6Q9Y6Q14.841
COMMD3Q9UBI14.811
NLGN2Q8NFZ44.811
SHROOM3Q8TF724.801
ARHGEF7Q141554.792
SLC9A3P487644.781
PSCDBPO607594.771
ABCA7Q8IZY24.741
ATP2B1P200204.730.033
ACE2Q9BYF14.720.032
GRK6P432504.711
OR8G1Q156174.711
GRM5P415944.701
ATP2A2P166154.671
KCNT2Q6UVM34.671
SLC4A7Q9Y6M74.671
SSTR5P353464.651
TMEM151BQ8IW704.641
SLC26A3P408794.631
WNV-NS5Q9Q6P44.620.075
GAS2L2Q8NHY34.621
SLC1A1P430054.611
BCRP112744.581
FRMPD1Q5SYB04.570.042
CES2O007484.551
CRHR1P349984.551
SLC22A3O757514.541
ASNSD1Q9NWL64.521
KLHDC7AQ5VTJ34.501
XKR7Q5GH724.441
MAP4P278164.421
SLC23A1Q9UHI74.421
TMIGD1Q6UXZ04.421
DGKIO759124.411
ARAP3Q8WWN84.401
CD46P155294.391
TJP3O950494.391
EVI5O604474.361
PRKCAP172524.341
GUCY1A2P334024.331
PLCB2Q007224.331
HPV49-L2P367624.321
ADGRG1Q9Y6534.311
RAPGEF2Q9Y4G84.281
DGKZQ135744.260.04*3, detectable in 2
SAPCD1Q5SSQ64.261
CNKSR2Q8WXI24.241
LNX1Q8TBB14.241
PRKD2Q9BZL64.231
PTENP604844.220.173
SHKBP1Q8TBC34.211
MCCP235084.171
PLEKHG7Q6ZR374.171
KIRREL1Q96J844.161
BANF1O755314.141
KCNT1Q5JUK34.141
CCRL2O004214.131
MAP2K2P365074.120.052
DGKKQ5KSL64.11*2, detectable in 1
APCP250544.100.002
CTNNB1P352224.101
FCHSD2O948684.101
HCN2Q9UL514.091
ZSCAN30Q86W114.081
PTENP60484(ALY)4024.070.164
CD226Q157624.061
RPS6KA1Q15418(TPO)7344.061
TTC24A2A3L64.041
BPIFA2Q96DR54.021
ACOT8O147344.011
ZNF599Q96NL34.011
LRRC4BQ9NT993.981
IQSEC2Q5JU853.961
PLCB1Q9NQ663.961
MUC3AQ025053.951
CXCR1P250243.941
SLC1A7O003413.941
TRPV3Q8NET83.941
REELD1A0A1B0GV853.931
SORCS3Q9UPU33.921
ACTN2P356093.911
RSBN1Q5VWQ03.911
GRIA2P422623.901
MUC3BQ9H1953.901
GAB3Q8WWW83.891
GHRHRQ026433.891
ATP2B4P236343.880.06*3, detectable in 2
RAPGEF6Q8TEU73.881
KIDINS220Q9ULH03.871
SEMA4FO957543.871
SH2D3CQ8N5H73.861
DFNB31Q9P2023.84*2, detectable in 1
KIRREL2Q6UWL63.841
RPS6KA1Q154183.830.256
CBPQ927933.83*2, detectable in 1
RNF130Q86XS83.821
KCNB1Q147213.781
SLCO1C1Q9NYB53.770.04*4, detectable in 2
VANGL1Q8TAA93.771
DLL1O005483.761
ITKQ088813.761
LRRC4Q9HBW13.761
SLC1A3P430033.761
STK16O757163.751
TJP2Q9UDY23.74*2, detectable in 1
RTKNQ9BST93.741
HPV30-E6P368093.73*2, detectable in 1
KCNJ1P480483.731
ADAM22Q9P0K13.721
GRIN1Q055863.721
MYOTQ9UBF93.721
KARS1Q150463.711
KCNA7Q96RP83.711
SLC2A3P111693.681
PDZRN3Q9UPQ73.661
PTGIRP431193.651
FKBP4Q027903.641
PPP1R13LQ8WUF53.641
FAT3Q8TDW73.632
TRIP6Q156543.631
HPV16-E6P031263.620.05*10, detectable in 2
FZD10Q9ULW23.621
GLAP062803.591
MARCHF4Q9P2E83.581
RPS6KA1Q15418(SEP)7323.57*5, detectable in 1
CITO145783.571
FZD1Q9UP383.571
TMEM215Q68D423.571
MAPK12P537783.560.012
DUSP5Q166903.551
GJC1P363833.551
EPHB3P547533.541
GRID2O434243.541
BAZ1AQ9NRL23.531
SDC2P347413.531
SHROOM4Q9ULL83.531
TRIM29Q141343.521
CYSLTR2Q9NS753.51*3, detectable in 1
HPV33-E6P064273.51*2, detectable in 1
LSM14AQ8ND563.511
PDGFRBP096193.511
NET1Q7Z6283.50*4, detectable in 1
KCNA5P224603.50*2, detectable in 1
RGS12O149243.49*2, detectable in 1
C3AR1Q165813.491
FOXI1Q129513.491
GDAQ9Y2T33.491
TRAF2Q129333.491
LNX2Q8N4483.481
HPV18-E6P06463not detectable5
HPV35-E6P27228not detectable4
MERS-EK9N5R3not detectable4
ARHGEF26Q96DR7not detectable3
FRMPD4Q14CM0not detectable3
HBV-HbcP03146not detectable3
HTLV1-TAX1P03409not detectable3
KCNA4P22459not detectable3
PLCB4Q15147not detectable3
SARS-CoV2-EP0DTC4not detectable3
ABCA1O95477not detectable2
AGMATQ9BSE5not detectable2
ARHGEF16Q5VV41not detectable2
CACNG4Q9UBN1not detectable2
DOCK4Q8N1I0not detectable2
FZD7O75084not detectable2
HPV16-E6P03126(TPO)156not detectable2
HPV51-E6P26554not detectable2
HPV59-E6Q81964not detectable2
HPV67-E6A4U7F2not detectable2
HPV73-E6Q82005not detectable2
HPV82-E6Q9IR59not detectable2
KIR3DL3Q8N743not detectable2
PBKQ96KB5not detectable2
RALBP1Q15311not detectable2
RASSF6Q6ZTQ3not detectable2
SARS-Cov-EP59637not detectable2
SARS-Cov2-3aP0DTC3not detectable2
SARS-Cov2-NP0DTC9not detectable2
SLC2A1P11166not detectable2
TANC2Q9HCD6not detectable2
ABCA2Q9BZC7not detectable1
ABCC6O95255not detectable1
ABRAXAS2Q15018not detectable1
ACOT6Q3I5F7not detectable1
ACVR2AP27037not detectable1
ADAM17P78536not detectable1
ADGRA1Q86SQ6not detectable1
ADGRA2Q96PE1not detectable1
ADGRA3Q8IWK6not detectable1
ADGRE5P48960not detectable1
ADRA1DP25100not detectable1
ADRB1P08588not detectable1
ADRB2P07550not detectable1
AKIP1Q9NQ31not detectable1
AMOTL1Q8IY63not detectable1
APBA1Q02410not detectable1
APPL1Q9UKG1not detectable1
AQP3Q92482not detectable1
AQP6Q13520not detectable1
ARHGAP6O43182not detectable1
ARVCFO00192not detectable1
ATRNL1Q5VV63not detectable1
AXIN1O15169not detectable1
CACNA1AO00555not detectable1
CACNG2Q9Y698not detectable1
CACNG8Q8WXS5not detectable1
CACYBPQ9HB71not detectable1
CAVIN3Q969G5not detectable1
CBY2Q8NA61not detectable1
CCDC134Q9H6E4not detectable1
CCL24O00175not detectable1
CDK18Q07002not detectable1
CES3Q6UWW8not detectable1
CGNQ9P2M7not detectable1
CIB2O75838not detectable1
CLDN1O95832not detectable1
CLDN10P78369not detectable1
CLDN14O95500not detectable1
CLDN18P56856not detectable1
CLDN19Q8N6F1not detectable1
CLDN2P57739not detectable1
CLDN20P56880not detectable1
CLDN3O15551not detectable1
CLDN4O14493not detectable1
CLDN7O95471not detectable1
CLDN8P56748not detectable1
CLDN9O95484not detectable1
CNTNAP2Q9UHC6not detectable1
CNTNAP4Q9C0A0not detectable1
CRB2Q5IJ48not detectable1
CRIPTQ9P021not detectable1
CSPG4Q6UVK1not detectable1
CTBP1Q13363not detectable1
CTNNA1P35221not detectable1
CTNNA2P26232not detectable1
CTNND2Q9UQB3not detectable1
DACT1Q9NYF0not detectable1
DCAF7P61962not detectable1
DCHS2Q6V1P9not detectable1
DENND5AQ6IQ26not detectable1
DGKHQ86XP1not detectable1
DUSP10Q9Y6W6not detectable1
EFNB1P52799not detectable1
EFNB3Q15768not detectable1
EGLN1Q9GZT9not detectable1
EPHA6Q9UF33not detectable1
EPHA7Q15375not detectable1
EPHB6O15197not detectable1
ERBB2P04626not detectable1
ERBB4Q15303not detectable1
EXOC4Q96A65not detectable1
EZH1Q92800not detectable1
FAM110BQ8TC76not detectable1
FAM110DQ8TAY7not detectable1
FAM167BQ9BTA0not detectable1
FAM71CQ8NEG0not detectable1
FAT1Q14517not detectable1
FLVCR1Q9Y5Y0not detectable1
FMNL3Q8IVF7not detectable1
FZD2Q14332not detectable1
FZD4Q9ULV1not detectable1
FZD8Q9H461not detectable1
GAGE12JA6NER3not detectable1
GJA1P17302not detectable1
GJD2Q9UKL4not detectable1
GJD4Q96KN9not detectable1
GOLT1AQ6ZVE7not detectable1
GOT1L1Q8NHS2not detectable1
GPR12P47775not detectable1
GPR6P46095not detectable1
GPRC6AQ5T6X5not detectable1
GRIA3P42263not detectable1
GRIK2Q13002not detectable1
GRIN2AQ12879not detectable1
GRIN2BQ13224not detectable1
GRIN2CQ14957not detectable1
GRIP1Q9Y3R0not detectable1
GYPCP04921not detectable1
HDAC7Q8WUI4not detectable1
HNRNPKP61978not detectable1
HPV18-E6P06463(TPO)156not detectable1
HPV31-E6P17386not detectable1
HPV33-E6P06427(TPO)147not detectable1
HPV35-E6P27228(TPO)147not detectable1
HSPA5P11021not detectable1
HTR2AP28223not detectable1
HTR2CP28335not detectable1
IGF1RP08069not detectable1
IGSF5Q9NSI5not detectable1
JAG1P78504not detectable1
JAM1Q9Y624not detectable1
JAM2P57087not detectable1
JAM3Q9BX67not detectable1
JUPP14923not detectable1
KCNA1Q09470not detectable1
KCNA6P17658not detectable1
KCNJ12Q14500not detectable1
KCNJ18B7U540not detectable1
KCNJ4P48050not detectable1
KCNJ9Q92806not detectable1
KCNV1Q6PIU1not detectable1
KCTD3Q9Y597not detectable1
KIF17Q9P2E2not detectable1
KITP10721not detectable1
LPAR1Q92633not detectable1
LPXNO60711not detectable1
LRP4O75096not detectable1
MAP7D2Q96T17not detectable1
MARCHF3Q86UD3not detectable1
MARCHF9Q86YJ5not detectable1
MAS1P04201not detectable1
MCM7P33993not detectable1
MKNK1Q9BUB5not detectable1
MLLT4P55196not detectable1
MMP24Q9Y5R2not detectable1
MTMR1Q13613not detectable1
MTNR1AP48039not detectable1
MYO18AQ92614not detectable1
MYOZ1Q9NP98not detectable1
MYOZ2Q9NPC6not detectable1
MYOZ3Q8TDC0not detectable1
MYPNQ86TC9not detectable1
NCBP2LA6PVI3not detectable1
NCF1P14598not detectable1
NDE1Q9NXR1not detectable1
NEBP20929not detectable1
NECTIN1Q15223not detectable1
NECTIN3Q9NQS3not detectable1
NF2P35240not detectable1
NHERF1O14745not detectable1
NHERF2Q15599not detectable1
NHERF3Q5T2W1not detectable1
NOS1APO75052not detectable1
NOSTRINQ8IVI9not detectable1
NPSR1Q6W5P4not detectable1
NRXN1Q9ULB1not detectable1
NRXN3Q9Y4C0rs746444206not detectable1
NRXN3Q9HDB5not detectable1
OR10G3Q8NGC4not detectable1
PALLSQ8WX93not detectable1
PDLIM2Q96JY6not detectable1
PDLIM4P50479iso2not detectable1
PDLIM4P50479not detectable1
PDLIM7Q9NR12not detectable1
PDZRN4Q6ZMN7not detectable1
PFKMP08237not detectable1
PKN2Q16513not detectable1
PKP4Q99569not detectable1
PLEKHA1Q9HB21not detectable1
PLEKHA2Q9HB19not detectable1
PLEKHH2Q8IVE3not detectable1
PLXNB1O43157not detectable1
POLR1DP0DPB6not detectable1
PPFIA1Q13136not detectable1
PPP1R3GB7ZBB8not detectable1
PRKACAP17612not detectable1
PRKNO60260not detectable1
PRLHRP49683not detectable1
PRR16Q569H4not detectable1
PTH2RP49190not detectable1
PTPRGP23470not detectable1
PTPRZ1P23471not detectable1
PTTG2Q9NZH5not detectable1
RAB9AP51151not detectable1
RAMP3O60896not detectable1
RASL11BQ9BPW5not detectable1
RCN1Q15293not detectable1
RCN2Q14257not detectable1
RNF146Q9NTX7not detectable1
RPS6KA1Q15418(TPO)733not detectable1
RRBP1Q9P2E9not detectable1
RSRC2Q7L4I2not detectable1
SBF1O95248not detectable1
SCN4AP35499not detectable1
SCN4BQ8IWT1not detectable1
SCN5AQ14524not detectable1
SCN8AQ9UQD0not detectable1
SDC3O75056not detectable1
SDC4P31431not detectable1
SDK2Q58EX2not detectable1
SEMA4CQ9C0C4not detectable1
SIPA1Q96FS4not detectable1
SLC16A1P53985not detectable1
SLC16A3O15427not detectable1
SLC16A7O60669not detectable1
SLC1A4P43007not detectable1
SLC1A5Q15758not detectable1
SLC2A7Q6PXP3not detectable1
SLC45A4Q5BKX6not detectable1
SLC6A3Q01959not detectable1
SLCO1B1Q9Y6L6not detectable1
SLCO2B1O94956not detectable1
SMCHD1A6NHR9not detectable1
SRCP12931not detectable1
TAGAPQ8N103not detectable1
TANC1Q9C0D5not detectable1
TBPL1P62380not detectable1
TECPR2O15040not detectable1
TGFAP01135not detectable1
TIAM1Q13009not detectable1
TMEM178AQ8NBL3not detectable1
TMEM178BH3BS89not detectable1
TMEM225BP0DP42not detectable1
TNRC6AQ8NDV7not detectable1
TNRC6BQ9UPQ9not detectable1
TRAF7Q6Q0C0not detectable1
TRIM50Q86XT4not detectable1
TRMT13Q9NUP7not detectable1
TRPM1Q7Z4N2not detectable1
TRPV6Q9H1D0not detectable1
TUBB4BP68371not detectable1
TYRO3Q06418not detectable1
TYRP1P17643not detectable1
U2AF2P26368not detectable1
UQCRC2P22695not detectable1
VAC14Q08AM6not detectable1
ZNF831Q5JPB2not detectable1





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