You are looking at the quantitative interactomic profile of the molecule of HTRA1


UniProt ID: Q92743
Molecule ID: HTRA1 (Link to all interactions of this molecule.)
Alternative name(s): HTRA PRSS11


The selection have 1 unique variants
non-modified profile

The selection have 1 unique fragments
365-480 fragment

The selection have 1 unique sites
PDZ sites

The current selection is unique





You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


Partners Experiment
IDUniProtModificationpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
CACNA1DQ016685.791
ZNF831Q5JPB25.701
NECTIN3Q9NQS35.621
TRAF7Q6Q0C05.611
YAP1P469375.581
FCHSD2O948685.501
NRXN3Q9HDB55.491
GNG4P501505.481
FAM71CQ8NEG05.381
JAG1P785045.371
NRXN3Q9Y4C0rs7464442065.321
CNTNAP2Q9UHC65.311
TECPR2O150405.291
NECTIN1Q152235.241
DCAF7P619625.221
JAM1Q9Y6245.151
GAS2L2Q8NHY35.141
CSPG4Q6UVK15.101
APBA1Q024105.071
TTC24A2A3L65.071
AMOTL1Q8IY635.051
RNF146Q9NTX75.051
CLDN8P567485.031
PTENP60484(ALY)4025.010.058
BANF1O755315.011
TMEM215Q68D425.002
MCM7P339934.991
JAM2P570874.971
MARCHF4Q9P2E84.961
PRKNO602604.961
HTR2AP282234.951
LNX2Q8N4484.942
GJC1P363834.931
ATRNL1Q5VV634.911
WWTR1Q9GZV54.911
SDC3O750564.901
NRXN1Q9ULB14.842
KCNA7Q96RP84.841
MARCHF9Q86YJ54.831
PRLHRP496834.821
PKP4Q995694.781
PRKD2Q9BZL64.771
AGMATQ9BSE54.751
GYPCP049214.741
ASIC3Q9UHC34.730.333
CNTNAP4Q9C0A04.722
PKN2Q165134.721
CTNND2Q9UQB34.711
TBC1D10AQ9BXI64.701
XKR7Q5GH724.691
NOS1APO750524.681
PTH1RQ034314.681
ABCA7Q8IZY24.641
FOXI1Q129514.641
JAM3Q9BX674.641
SARS-Cov-EP596374.620.055
PDLIM4P50479iso24.621
TGFAP011354.621
LNX1Q8TBB14.612
EPHA6Q9UF334.611
KCNV1Q6PIU14.611
ARVCFO001924.602
DUSP10Q9Y6W64.601
EXOC4Q96A654.601
GJD2Q9UKL44.601
KIDINS220Q9ULH04.601
RPS6KA1Q15418(TPO)7344.590.095
EPHB6O151974.591
FZD10Q9ULW24.571
CAPN6Q9Y6Q14.551
SLC45A4Q5BKX64.551
MERS-EK9N5R34.540.177
CACNA1AO005554.531
NF2P352404.511
SCN5AQ145244.511
SDK2Q58EX24.511
RGS12O149244.500.103
IQSEC2Q5JU854.501
MMP24Q9Y5R24.501
EFNB3Q157684.491
IGSF5Q9NSI54.491
RNF130Q86XS84.491
GOT1L1Q8NHS24.481
BCRP112744.471
FAM167BQ9BTA04.471
SDC2P347414.471
SARS-CoV2-EP0DTC44.460.096
EVI5O604474.451
SLC6A3Q019594.451
TRPV6Q9H1D04.451
WNV-NS5Q9Q6P44.440.084
CCRL2O004214.441
TRIM29Q141344.421
FZD2Q143324.411
PTPRGP234704.411
PTPRZ1P234714.411
SDC4P314314.411
SLC1A4P430074.411
RPS6KA1Q154184.400.19*20, detectable in 19
DFNB31Q9P2024.40*2, detectable in 1
CLDN2P577394.401
PTPN18Q999524.401
TMEM178AQ8NBL34.401
GJD4Q96KN94.381
EFNB1P527994.371
CACNG4Q9UBN14.362
CES2O007484.361
EPHA7Q153754.361
MARCHF3Q86UD34.351
CLDN14O955004.341
FZD1Q9UP384.341
GRASPQ7Z6J24.33*2, detectable in 1
PTENP604844.320.037
ABCA1O954774.320.063
GRIN1Q055864.322
ADGRA3Q8IWK64.321
CLDN18P568564.321
FAM110BQ8TC764.321
JUPP149234.321
TMEM178BH3BS894.321
TMEM225BP0DP424.311
PDZRN3Q9UPQ74.302
USH1CQ9Y6N94.302
FZD4Q9ULV14.301
LPAR1Q926334.301
ADGRA2Q96PE14.271
PDGFRBP096194.271
PPFIA1Q131364.271
ADGRA1Q86SQ64.261
RAMP3O608964.261
DCHS2Q6V1P94.251
GRIA2P422624.251
VAC14Q08AM64.251
RPS6KA1Q15418(SEP)7324.230.45*17, detectable in 15
APCP250544.210.013
C3AR1Q165814.201
RAPGEF2Q9Y4G84.182
CRB2Q5IJ484.181
GRK6P432504.181
HTR2CP283354.181
PLCB4Q151474.170.052
CLDN4O144934.171
EZH1Q928004.171
MYOTQ9UBF94.171
HDAC7Q8WUI44.161
PLEKHH2Q8IVE34.161
TRPV3Q8NET84.161
AKIP1Q9NQ314.151
CIB2O758384.151
NPSR1Q6W5P44.151
HPV59-E6Q819644.14*3, detectable in 2
CLDN3O155514.141
PTH2RP491904.141
U2AF2P263684.141
ARHGAP6O431824.131
ERBB4Q153034.131
TJP3O950494.122
PLXNB1O431574.121
SLC15A5A6NIM64.110.21*6, detectable in 4
ABCA2Q9BZC74.111
EPHB3P547534.111
TYRP1P176434.111
OTULINQ96BN84.070.032
BPIFA2Q96DR54.061
PRR16Q569H44.061
DLL1O005484.042
DACT1Q9NYF04.041
SLC2A3P111694.041
NEBP209294.031
TAGAPQ8N1034.031
HPV73-E6Q820054.000.102
CDK18Q070024.001
FAT1Q145174.001
GOLT1AQ6ZVE74.001
HPV49-L2P367623.992
MYOZ1Q9NP983.991
ZSCAN30Q86W113.991
KCTD3Q9Y5973.982
ABCC6O952553.981
GRIA3P422633.981
RCN2Q142573.981
CLDN10P783693.971
UQCRC2P226953.971
KARS1Q150463.951
RASL11BQ9BPW53.951
RAPGEF6Q8TEU73.942
CLDN1O958323.941
HTLV1-TAX1P034093.930.188
CAVIN3Q969G53.931
PTGIRP431193.931
ARHGEF7Q141553.922
ADAM22Q9P0K13.921
SLC22A11Q9NSA03.921
TRPC5Q9UL623.921
KCNA6P176583.911
PTTG2Q9NZH53.901
ABCC4O154393.890.06*6, detectable in 2
CD46P155293.891
COMMD3Q9UBI13.891
SCN4AP354993.891
SEMA4FO957543.891
TBPL1P623803.891
SLC1A5Q157583.861
TMEM151BQ8IW703.861
FKBP4Q027903.851
KCNJ18B7U5403.851
SEMA4CQ9C0C43.851
CNKSR2Q8WXI23.842
CLDN9O954843.841
MYOZ3Q8TDC03.841
RRBP1Q9P2E93.841
RPS6KA1Q15418(TPO)7333.820.104
GRIN2CQ149573.821
SORCS3Q9UPU33.821
ATP2B4P236343.810.08*3, detectable in 2
DGKZQ135743.800.23*4, detectable in 3
ATP2B1P200203.790.042
MAP7D2Q96T173.791
FRMPD4Q14CM03.770.18*4, detectable in 3
EGLN1Q9GZT93.771
GUCY1A2P334023.771
FMNL3Q8IVF73.761
SLC1A7O003413.761
RASSF6Q6ZTQ33.75*2, detectable in 1
GLAP062803.741
RSBN1Q5VWQ03.741
HPV30-E6P368093.73*2, detectable in 1
PODXLO005923.731
SLC23A1Q9UHI73.731
SLC34A1Q064953.731
SLCO1C1Q9NYB53.720.06*6, detectable in 3
CLDN7O954713.721
NLGN4XQ8N0W43.721
SLC4A7Q9Y6M73.711
NET1Q7Z6283.700.14*9, detectable in 6
IGF1RP080693.691
MYPNQ86TC93.691
PDLIM7Q9NR123.682
LSM14AQ8ND563.671
PPP1R3GB7ZBB83.671
ZNF599Q96NL33.671
CCL24O001753.661
ARHGAP17Q68EM73.651
DGKIO759123.651
ABRAXAS2Q150183.641
CLDN20P568803.641
DLGAP4Q9Y2H03.631
ADRB2P075503.622
ATP2A2P166153.621
SLC5A12Q1EHB43.621
TRPM1Q7Z4N23.621
PDZRN4Q6ZMN73.612
MAS1P042013.611
SLC22A3O757513.611
DENND5AQ6IQ263.601
NLGN2Q8NFZ43.601
ERBB2P046263.591
OR10G3Q8NGC43.581
RPS6KA3P518123.581
TUBB4BP683713.581
ADAM17P785363.561
TRIP6Q156543.561
GHRHRQ026433.551
REELD1A0A1B0GV853.551
KCNB1Q147213.531
PLEKHG7Q6ZR373.521
MTMR1Q136133.512
SLCO1B1Q9Y6L63.511
GRIP1Q9Y3R03.501
RCN1Q152933.501
SLC22A9Q8IVM83.491
HPV33-E6P064273.48*3, detectable in 2
HPV16-E6P03126not detectable16
HPV18-E6P06463not detectable10
HPV35-E6P27228not detectable9
CBPQ92793not detectable6
HPV16-E6P03126(TPO)156not detectable5
CYSLTR2Q9NS75not detectable4
ACE2Q9BYF1not detectable3
FRMPD1Q5SYB0not detectable3
HBV-HbcP03146not detectable3
HPV82-E6Q9IR59not detectable3
RALBP1Q15311not detectable3
ARHGEF16Q5VV41not detectable2
ARHGEF26Q96DR7not detectable2
CACYBPQ9HB71not detectable2
CFTRP13569not detectable2
CGNQ9P2M7not detectable2
DGKKQ5KSL6not detectable2
DOCK4Q8N1I0not detectable2
FZD7O75084not detectable2
GRIN2BQ13224not detectable2
HPV31-E6P17386not detectable2
HPV51-E6P26554not detectable2
HPV67-E6A4U7F2not detectable2
KCNA4P22459not detectable2
KCNA5P22460not detectable2
KIR3DL3Q8N743not detectable2
MAP2K2P36507not detectable2
MAPK12P53778not detectable2
MYO18AQ92614not detectable2
NHERF1O14745not detectable2
NHERF2Q15599not detectable2
NHERF3Q5T2W1not detectable2
PBKQ96KB5not detectable2
PDLIM2Q96JY6not detectable2
PDLIM4P50479not detectable2
PSCDBPO60759not detectable2
RTKNQ9BST9not detectable2
SARS-Cov2-3aP0DTC3not detectable2
SARS-Cov2-NP0DTC9not detectable2
SHKBP1Q8TBC3not detectable2
SHROOM3Q8TF72not detectable2
SHROOM4Q9ULL8not detectable2
SLC2A1P11166not detectable2
TIAM1Q13009not detectable2
TJP2Q9UDY2not detectable2
ACOT6Q3I5F7not detectable1
ACOT8O14734not detectable1
ACTN2P35609not detectable1
ACVR2AP27037not detectable1
ADGRE5P48960not detectable1
ADGRG1Q9Y653not detectable1
ADRA1DP25100not detectable1
ADRB1P08588not detectable1
AKAP10O43572not detectable1
APPL1Q9UKG1not detectable1
AQP3Q92482not detectable1
AQP6Q13520not detectable1
ARAP3Q8WWN8not detectable1
ASNSD1Q9NWL6not detectable1
AXIN1O15169not detectable1
BAZ1AQ9NRL2not detectable1
CACNG2Q9Y698not detectable1
CACNG8Q8WXS5not detectable1
CBY2Q8NA61not detectable1
CCDC134Q9H6E4not detectable1
CD226Q15762not detectable1
CES3Q6UWW8not detectable1
CITO14578not detectable1
CLDN19Q8N6F1not detectable1
CRHR1P34998not detectable1
CRIPTQ9P021not detectable1
CTBP1Q13363not detectable1
CTNNA1P35221not detectable1
CTNNA2P26232not detectable1
CTNNB1P35222not detectable1
CXCR1P25024not detectable1
DGKHQ86XP1not detectable1
DUSP5Q16690not detectable1
FAM110DQ8TAY7not detectable1
FAT3Q8TDW7not detectable1
FLVCR1Q9Y5Y0not detectable1
FZD8Q9H461not detectable1
GAB3Q8WWW8not detectable1
GAGE12JA6NER3not detectable1
GDAQ9Y2T3not detectable1
GJA1P17302not detectable1
GPR12P47775not detectable1
GPR6P46095not detectable1
GPRC6AQ5T6X5not detectable1
GRID2O43424not detectable1
GRIK2Q13002not detectable1
GRIN2AQ12879not detectable1
GRM5P41594not detectable1
HCN2Q9UL51not detectable1
HNRNPKP61978not detectable1
HPV18-E6P06463(TPO)156not detectable1
HPV33-E6P06427(TPO)147not detectable1
HPV35-E6P27228(TPO)147not detectable1
HSPA5P11021not detectable1
ITKQ08881not detectable1
KCNA1Q09470not detectable1
KCNJ1P48048not detectable1
KCNJ12Q14500not detectable1
KCNJ4P48050not detectable1
KCNJ9Q92806not detectable1
KCNT1Q5JUK3not detectable1
KCNT2Q6UVM3not detectable1
KIF17Q9P2E2not detectable1
KIRREL1Q96J84not detectable1
KIRREL2Q6UWL6not detectable1
KITP10721not detectable1
KLHDC7AQ5VTJ3not detectable1
LPXNO60711not detectable1
LRP4O75096not detectable1
LRRC4Q9HBW1not detectable1
LRRC4BQ9NT99not detectable1
MAP4P27816not detectable1
MCCP23508not detectable1
MKNK1Q9BUB5not detectable1
MLLT4P55196not detectable1
MTNR1AP48039not detectable1
MUC3AQ02505not detectable1
MUC3BQ9H195not detectable1
MYOZ2Q9NPC6not detectable1
NCBP2LA6PVI3not detectable1
NCF1P14598not detectable1
NDE1Q9NXR1not detectable1
NOSTRINQ8IVI9not detectable1
OR8G1Q15617not detectable1
PALLSQ8WX93not detectable1
PFKMP08237not detectable1
PLCB1Q9NQ66not detectable1
PLCB2Q00722not detectable1
PLEKHA1Q9HB21not detectable1
PLEKHA2Q9HB19not detectable1
POLR1DP0DPB6not detectable1
PPP1R13LQ8WUF5not detectable1
PRKACAP17612not detectable1
PRKCAP17252not detectable1
RAB9AP51151not detectable1
RSRC2Q7L4I2not detectable1
SAPCD1Q5SSQ6not detectable1
SBF1O95248not detectable1
SCN4BQ8IWT1not detectable1
SCN8AQ9UQD0not detectable1
SH2D3CQ8N5H7not detectable1
SIPA1Q96FS4not detectable1
SLC15A2Q16348not detectable1
SLC16A1P53985not detectable1
SLC16A3O15427not detectable1
SLC16A7O60669not detectable1
SLC17A1Q14916not detectable1
SLC1A1P43005not detectable1
SLC1A3P43003not detectable1
SLC22A12Q96S37not detectable1
SLC26A3P40879not detectable1
SLC2A7Q6PXP3not detectable1
SLC9A3P48764not detectable1
SLCO1A2P46721not detectable1
SLCO2B1O94956not detectable1
SMCHD1A6NHR9not detectable1
SRCP12931not detectable1
SSTR5P35346not detectable1
STK16O75716not detectable1
TANC1Q9C0D5not detectable1
TANC2Q9HCD6not detectable1
TMIGD1Q6UXZ0not detectable1
TNRC6AQ8NDV7not detectable1
TNRC6BQ9UPQ9not detectable1
TRAF2Q12933not detectable1
TRIM50Q86XT4not detectable1
TRMT13Q9NUP7not detectable1
TYRO3Q06418not detectable1
UNC93AQ86WB7not detectable1
VANGL1Q8TAA9not detectable1





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