You are looking at the quantitative interactomic profile of the molecule of NHERF4


UniProt ID: Q86UT5
Molecule ID: NHERF4 (Link to all interactions of this molecule.)
Alternative name(s): PDZD3 IKEPP PDZK2 DLNB27


The selection have 1 unique variants
non-modified profile

The selection have 4 unique sites
PDZ_1 sites
PDZ_2 sites
PDZ_3 sites
PDZ_4 sites







You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


Partners Experiment
IDUniProtModificationpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
PTTG2Q9NZH54.90*3, detectable in 1
HPV33-E6P06427(TPO)1474.60*3, detectable in 1
CIB2O758384.58*3, detectable in 1
FRMPD1Q5SYB04.560.08*6, detectable in 2
SLC15A5A6NIM64.560.16*14, detectable in 8
SLC22A11Q9NSA04.55*3, detectable in 1
GUCY1A2P334024.54*3, detectable in 1
PTGIRP431194.54*3, detectable in 1
HPV33-E6P064274.520.14*8, detectable in 3
OR8G1Q156174.51*3, detectable in 1
TMEM151BQ8IW704.51*3, detectable in 1
ABCC4O154394.440.19*12, detectable in 8
SARS-Cov2-3aP0DTC34.43*8, detectable in 2
KCNV1Q6PIU14.43*3, detectable in 1
MYOTQ9UBF94.41*3, detectable in 1
ATP2A2P166154.39*3, detectable in 1
TRPC5Q9UL624.38*3, detectable in 1
DFNB31Q9P2024.370.47*6, detectable in 2
CTNNA2P262324.37*3, detectable in 1
GHRHRQ026434.35*3, detectable in 1
SLC5A12Q1EHB44.35*3, detectable in 1
WWTR1Q9GZV54.340.12*3, detectable in 2
MKNK1Q9BUB54.34*3, detectable in 1
PKN2Q165134.34*3, detectable in 1
RAMP3O608964.33*3, detectable in 1
PRKNO602604.30*3, detectable in 1
SLC22A9Q8IVM84.30*3, detectable in 1
SSTR5P353464.30*3, detectable in 1
MYPNQ86TC94.29*3, detectable in 1
PPP1R3GB7ZBB84.29*3, detectable in 1
HPV59-E6Q819644.28*8, detectable in 1
AKAP10O435724.28*3, detectable in 1
CD46P155294.28*3, detectable in 1
FAM167BQ9BTA04.27*3, detectable in 1
COMMD3Q9UBI14.23*3, detectable in 1
RPS6KA1Q15418(TPO)7344.23*3, detectable in 1
DOCK4Q8N1I04.220.08*7, detectable in 3
GRK6P432504.22*3, detectable in 1
HPV16-E6P031264.210.18*37, detectable in 19
SLC23A1Q9UHI74.210.32*3, detectable in 2
KIF17Q9P2E24.21*3, detectable in 1
MYOZ1Q9NP984.20*3, detectable in 1
TTC24A2A3L64.20*3, detectable in 1
UQCRC2P226954.20*3, detectable in 1
SLC16A3O154274.19*3, detectable in 1
ABCA2Q9BZC74.18*3, detectable in 1
WNV-NS5Q9Q6P44.17*21, detectable in 1
YAP1P469374.16*3, detectable in 2
GNG4P501504.160.40*3, detectable in 2
ARHGAP17Q68EM74.16*3, detectable in 1
ATP2B1P200204.150.24*8, detectable in 2
PLEKHH2Q8IVE34.150.26*3, detectable in 2
SHROOM3Q8TF724.15*3, detectable in 1
OTULINQ96BN84.140.19*8, detectable in 3
HPV16-E6P03126(TPO)1564.140.22*7, detectable in 2
ASIC3Q9UHC34.140.60*10, detectable in 7
CACNA1DQ016684.130.39*3, detectable in 2
GRM5P415944.13*3, detectable in 1
PRKD2Q9BZL64.120.15*3, detectable in 2
MCCP235084.12*3, detectable in 1
MCM7P339934.12*3, detectable in 1
HPV49-L2P367624.110.58*3, detectable in 2
RCN2Q142574.10*3, detectable in 1
RPS6KA3P518124.100.503
SLC22A12Q96S374.10*3, detectable in 1
FAM71CQ8NEG04.090.59*3, detectable in 2
CES2O007484.09*3, detectable in 1
SLCO1C1Q9NYB54.090.22*14, detectable in 6
MAPK12P537784.080.23*6, detectable in 2
MYOZ3Q8TDC04.080.23*3, detectable in 2
TBPL1P623804.08*3, detectable in 1
SLC17A1Q149164.07*3, detectable in 1
GJD4Q96KN94.06*3, detectable in 1
KCNT2Q6UVM34.06*3, detectable in 1
CTBP1Q133634.05*3, detectable in 1
CTNNB1P352224.04*5, detectable in 2
CLDN8P567484.03*3, detectable in 1
CACNA1AO005554.01*3, detectable in 1
SLC34A1Q064954.01*3, detectable in 1
PLXNB1O431574.00*3, detectable in 1
SLC2A7Q6PXP34.00*3, detectable in 1
RNF130Q86XS83.990.11*3, detectable in 2
NF2P352403.990.33*3, detectable in 2
GLAP062803.99*3, detectable in 1
SLC1A1P430053.99*3, detectable in 1
PDLIM4P50479iso23.98*3, detectable in 1
PPFIA1Q131363.98*3, detectable in 1
TRIM50Q86XT43.98*3, detectable in 1
RCN1Q152933.970.04*3, detectable in 2
FKBP4Q027903.97*3, detectable in 1
TBC1D10AQ9BXI63.97*3, detectable in 1
HCN2Q9UL513.96*3, detectable in 1
SLC15A2Q163483.950.32*3, detectable in 2
FZD1Q9UP383.95*3, detectable in 1
LRRC4Q9HBW13.95*3, detectable in 1
REELD1A0A1B0GV853.95*3, detectable in 1
CLDN2P577393.940.05*3, detectable in 2
KCNT1Q5JUK33.940.05*3, detectable in 2
ATRNL1Q5VV633.94*3, detectable in 1
TRPV6Q9H1D03.94*3, detectable in 1
CAPN6Q9Y6Q13.94*3, detectable in 1
KCNA7Q96RP83.94*3, detectable in 1
SLC22A3O757513.94*3, detectable in 1
VAC14Q08AM63.920.15*3, detectable in 2
FZD2Q143323.92*3, detectable in 1
MYOZ2Q9NPC63.92*3, detectable in 1
GJC1P363833.910.33*3, detectable in 2
ADAM22Q9P0K13.91*3, detectable in 1
FZD10Q9ULW23.91*3, detectable in 1
SCN8AQ9UQD03.91*3, detectable in 1
SLCO1A2P467213.91*3, detectable in 1
SORCS3Q9UPU33.910.313
GRASPQ7Z6J23.90*7, detectable in 1
ADGRA1Q86SQ63.90*3, detectable in 1
SLC1A4P430073.90*3, detectable in 1
PTENP604843.900.29*14, detectable in 3
HBV-HbcP031463.900.08*11, detectable in 5
FRMPD4Q14CM03.90*11, detectable in 1
CFTRP135693.89*6, detectable in 1
SH2D3CQ8N5H73.890.29*3, detectable in 2
GPRC6AQ5T6X53.88*3, detectable in 1
SCN5AQ145243.88*3, detectable in 1
ACTN2P356093.88*3, detectable in 1
ADRB2P075503.88*3, detectable in 1
IGF1RP080693.88*3, detectable in 1
TMIGD1Q6UXZ03.88*3, detectable in 1
BANF1O755313.870.26*3, detectable in 2
RSRC2Q7L4I23.870.04*3, detectable in 2
ADGRA3Q8IWK63.87*3, detectable in 1
ASNSD1Q9NWL63.87*3, detectable in 1
CDK18Q070023.87*3, detectable in 1
PDGFRBP096193.860.153
SCN4AP354993.860.10*3, detectable in 2
HNRNPKP619783.860.14*3, detectable in 2
ABCA7Q8IZY23.86*3, detectable in 1
CCDC134Q9H6E43.86*3, detectable in 1
SLC1A7O003413.85*3, detectable in 1
BPIFA2Q96DR53.85*3, detectable in 1
NDE1Q9NXR13.85*3, detectable in 1
PTH2RP491903.85*3, detectable in 1
CRHR1P349983.840.03*3, detectable in 2
RASL11BQ9BPW53.840.07*3, detectable in 2
MLLT4P551963.84*3, detectable in 1
JAM1Q9Y6243.84*3, detectable in 1
PLCB2Q007223.84*3, detectable in 1
RNF146Q9NTX73.830.183
TANC1Q9C0D53.83*3, detectable in 1
EPHA7Q153753.820.223
DGKKQ5KSL63.81*7, detectable in 1
CLDN18P568563.810.183
CLDN4O144933.810.11*3, detectable in 2
CNTNAP4Q9C0A03.810.29*3, detectable in 2
EXOC4Q96A653.810.18*3, detectable in 2
POLR1DP0DPB63.81*3, detectable in 1
RAB9AP511513.81*3, detectable in 1
CBPQ927933.800.06*7, detectable in 4
PRLHRP496833.800.16*3, detectable in 2
EZH1Q928003.80*3, detectable in 1
HSPA5P110213.80*3, detectable in 1
NCBP2LA6PVI33.80*3, detectable in 1
GAGE12JA6NER33.79*3, detectable in 1
CSPG4Q6UVK13.780.27*3, detectable in 2
KCNB1Q147213.780.24*3, detectable in 2
NECTIN3Q9NQS33.780.29*3, detectable in 2
ACOT8O147343.78*3, detectable in 1
GRIA2P422623.78*3, detectable in 1
PRKCAP172523.78*3, detectable in 1
HPV35-E6P272283.78*14, detectable in 1
KIDINS220Q9ULH03.77*3, detectable in 1
CLDN14O955003.760.19*3, detectable in 2
FLVCR1Q9Y5Y03.760.16*3, detectable in 2
GRIA3P422633.760.19*3, detectable in 2
ACOT6Q3I5F73.76*3, detectable in 1
NLGN4XQ8N0W43.76*3, detectable in 1
TRAF2Q129333.76*3, detectable in 1
PTPRGP234703.75*3, detectable in 1
SLC9A3P487643.75*3, detectable in 1
RRBP1Q9P2E93.740.23*3, detectable in 2
ITKQ088813.740.17*3, detectable in 2
CXCR1P250243.74*3, detectable in 1
FAM110BQ8TC763.74*3, detectable in 1
HTLV1-TAX1P034093.740.12*15, detectable in 3
CACNG8Q8WXS53.730.193
DENND5AQ6IQ263.730.14*3, detectable in 2
HPV35-E6P27228(TPO)1473.730.13*3, detectable in 2
FCHSD2O948683.73*3, detectable in 1
SHKBP1Q8TBC33.73*3, detectable in 1
RPS6KA1Q15418(SEP)7323.730.10*18, detectable in 2
EPHB3P547533.720.20*3, detectable in 2
HTR2CP283353.72*3, detectable in 1
TJP3O950493.72*3, detectable in 1
ZNF599Q96NL33.72*3, detectable in 1
PTENP60484(ALY)4023.720.10*13, detectable in 2
ACE2Q9BYF13.710.17*6, detectable in 3
APCP250543.710.18*6, detectable in 2
EPHB6O151973.71*3, detectable in 1
FOXI1Q129513.71*3, detectable in 1
GRIN2CQ149573.71*3, detectable in 1
TRIM29Q141343.700.10*3, detectable in 2
KIRREL1Q96J843.70*3, detectable in 1
PTPRZ1P234713.70*3, detectable in 1
SEMA4CQ9C0C43.70*3, detectable in 1
CLDN20P568803.69*3, detectable in 1
PDZRN4Q6ZMN73.69*3, detectable in 1
RPS6KA1Q15418(TPO)7333.69*3, detectable in 1
TRIP6Q156543.69*3, detectable in 1
ABCA1O954773.680.21*6, detectable in 2
HDAC7Q8WUI43.680.10*3, detectable in 2
TMEM178AQ8NBL33.680.06*3, detectable in 2
ADAM17P785363.68*3, detectable in 1
BCRP112743.68*3, detectable in 1
CBY2Q8NA613.67*3, detectable in 1
SLC26A3P408793.67*3, detectable in 1
GOT1L1Q8NHS23.660.16*3, detectable in 2
ZNF831Q5JPB23.66*3, detectable in 1
CLDN3O155513.66*3, detectable in 1
TRPM1Q7Z4N23.66*3, detectable in 1
TYRO3Q064183.66*3, detectable in 1
TRAF7Q6Q0C03.650.03*3, detectable in 2
SLC6A3Q019593.65*3, detectable in 1
DLGAP4Q9Y2H03.65*3, detectable in 1
MUC3BQ9H1953.64*3, detectable in 1
U2AF2P263683.64*3, detectable in 1
RPS6KA1Q154183.640.15*22, detectable in 3
OR10G3Q8NGC43.63*3, detectable in 1
TNRC6BQ9UPQ93.63*3, detectable in 1
CGNQ9P2M73.62*3, detectable in 1
CLDN1O958323.62*3, detectable in 1
KIRREL2Q6UWL63.62*3, detectable in 1
NPSR1Q6W5P43.62*3, detectable in 1
PTPN18Q999523.62*3, detectable in 1
LSM14AQ8ND563.61*3, detectable in 1
TJP2Q9UDY23.600.13*7, detectable in 2
ARHGAP6O431823.60*3, detectable in 1
GJD2Q9UKL43.60*3, detectable in 1
HPV18-E6P06463(TPO)1563.60*3, detectable in 1
MAP7D2Q96T173.60*3, detectable in 1
USH1CQ9Y6N93.60*3, detectable in 1
CAVIN3Q969G53.59*3, detectable in 1
DUSP5Q166903.59*3, detectable in 1
SDK2Q58EX23.59*3, detectable in 1
SRCP129313.59*3, detectable in 1
NET1Q7Z6283.59*14, detectable in 1
RGS12O149243.57*6, detectable in 1
PKP4Q995693.57*3, detectable in 1
SDC2P347413.57*3, detectable in 1
PLCB1Q9NQ663.56*3, detectable in 1
PRKACAP176123.56*3, detectable in 1
PTH1RQ034313.56*3, detectable in 1
SLC2A3P111693.56*3, detectable in 1
ARAP3Q8WWN83.55*3, detectable in 1
CTNND2Q9UQB33.55*3, detectable in 1
LNX2Q8N4483.55*3, detectable in 1
CCRL2O004213.53*3, detectable in 1
CRIPTQ9P0213.53*3, detectable in 1
GRIN2BQ132243.53*3, detectable in 1
MAP2K2P365073.52*7, detectable in 1
HPV18-E6P064633.52*14, detectable in 1
ABCC6O952553.51*3, detectable in 1
MTNR1AP480393.51*3, detectable in 1
MUC3AQ025053.51*3, detectable in 1
PDZRN3Q9UPQ73.49*3, detectable in 1
CLDN19Q8N6F13.49*3, detectable in 1
SCN4BQ8IWT13.49*3, detectable in 1
SLC4A7Q9Y6M73.49*3, detectable in 1
MARCHF9Q86YJ53.48*3, detectable in 2
IQSEC2Q5JU853.48*3, detectable in 1
KCNJ4P480503.48*3, detectable in 1
PALLSQ8WX933.48*3, detectable in 1
SLC45A4Q5BKX63.48*3, detectable in 1
LNX1Q8TBB13.47*3, detectable in 1
MMP24Q9Y5R23.47*3, detectable in 1
RALBP1Q153113.36*10, detectable in 1
ACVR2AP270373.35*3, detectable in 1
MERS-EK9N5R3not detectable14
CYSLTR2Q9NS75not detectable11
DGKZQ13574not detectable11
SARS-CoV2-EP0DTC4not detectable11
ATP2B4P23634not detectable10
SARS-Cov-EP59637not detectable8
SARS-Cov2-NP0DTC9not detectable8
ARHGEF26Q96DR7not detectable8
HPV82-E6Q9IR59not detectable8
KCNA4P22459not detectable8
PLCB4Q15147not detectable8
ARHGEF16Q5VV41not detectable7
FZD7O75084not detectable7
HPV30-E6P36809not detectable7
HPV51-E6P26554not detectable7
HPV67-E6A4U7F2not detectable7
HPV73-E6Q82005not detectable7
KCNA5P22460not detectable7
PBKQ96KB5not detectable7
RASSF6Q6ZTQ3not detectable7
CACNG4Q9UBN1not detectable6
SLC2A1P11166not detectable6
KIR3DL3Q8N743not detectable6
SNX27Q96L92not detectable6
AGMATQ9BSE5not detectable5
ARHGEF7Q14155not detectable5
FAT3Q8TDW7not detectable5
TANC2Q9HCD6not detectable5
HPV31-E6P17386not detectable4
ABRAXAS2Q15018not detectable3
ADGRA2Q96PE1not detectable3
ADGRE5P48960not detectable3
ADGRG1Q9Y653not detectable3
ADRA1DP25100not detectable3
ADRB1P08588not detectable3
AKIP1Q9NQ31not detectable3
AMOTL1Q8IY63not detectable3
APBA1Q02410not detectable3
APPL1Q9UKG1not detectable3
AQP3Q92482not detectable3
AQP6Q13520not detectable3
ARVCFO00192not detectable3
AXIN1O15169not detectable3
BAZ1AQ9NRL2not detectable3
C3AR1Q16581not detectable3
CACNG2Q9Y698not detectable3
CACYBPQ9HB71not detectable3
CCL24O00175not detectable3
CD226Q15762not detectable3
CES3Q6UWW8not detectable3
CITO14578not detectable3
CLDN10P78369not detectable3
CLDN7O95471not detectable3
CLDN9O95484not detectable3
CNKSR2Q8WXI2not detectable3
CNTNAP2Q9UHC6not detectable3
CRB2Q5IJ48not detectable3
CTNNA1P35221not detectable3
DACT1Q9NYF0not detectable3
DCAF7P61962not detectable3
DCHS2Q6V1P9not detectable3
DGKHQ86XP1not detectable3
DGKIO75912not detectable3
DLL1O00548not detectable3
DUSP10Q9Y6W6not detectable3
EFNB1P52799not detectable3
EFNB3Q15768not detectable3
EGLN1Q9GZT9not detectable3
EPHA6Q9UF33not detectable3
ERBB2P04626not detectable3
ERBB4Q15303not detectable3
EVI5O60447not detectable3
FAM110DQ8TAY7not detectable3
FAT1Q14517not detectable3
FMNL3Q8IVF7not detectable3
FZD4Q9ULV1not detectable3
FZD8Q9H461not detectable3
GAB3Q8WWW8not detectable3
GAS2L2Q8NHY3not detectable3
GDAQ9Y2T3not detectable3
GJA1P17302not detectable3
GOLT1AQ6ZVE7not detectable3
GPR12P47775not detectable3
GPR6P46095not detectable3
GRID2O43424not detectable3
GRIK2Q13002not detectable3
GRIN1Q05586not detectable3
GRIN2AQ12879not detectable3
GRIP1Q9Y3R0not detectable3
GYPCP04921not detectable3
HTR2AP28223not detectable3
IGSF5Q9NSI5not detectable3
JAG1P78504not detectable3
JAM2P57087not detectable3
JAM3Q9BX67not detectable3
JUPP14923not detectable3
KARS1Q15046not detectable3
KCNA1Q09470not detectable3
KCNA6P17658not detectable3
KCNJ1P48048not detectable3
KCNJ12Q14500not detectable3
KCNJ18B7U540not detectable3
KCNJ9Q92806not detectable3
KCTD3Q9Y597not detectable3
KITP10721not detectable3
KLHDC7AQ5VTJ3not detectable3
LPAR1Q92633not detectable3
LPXNO60711not detectable3
LRP4O75096not detectable3
LRRC4BQ9NT99not detectable3
MAP4P27816not detectable3
MARCHF3Q86UD3not detectable3
MARCHF4Q9P2E8not detectable3
MAS1P04201not detectable3
MTMR1Q13613not detectable3
MYO18AQ92614not detectable3
NCF1P14598not detectable3
NEBP20929not detectable3
NECTIN1Q15223not detectable3
NHERF1O14745not detectable3
NHERF2Q15599not detectable3
NHERF3Q5T2W1not detectable3
NLGN2Q8NFZ4not detectable3
NOS1APO75052not detectable3
NOSTRINQ8IVI9not detectable3
NRXN1Q9ULB1not detectable3
NRXN3Q9Y4C0rs746444206not detectable3
NRXN3Q9HDB5not detectable3
PDLIM2Q96JY6not detectable3
PDLIM4P50479not detectable3
PDLIM7Q9NR12not detectable3
PFKMP08237not detectable3
PLEKHA1Q9HB21not detectable3
PLEKHA2Q9HB19not detectable3
PLEKHG7Q6ZR37not detectable3
PODXLO00592not detectable3
PPP1R13LQ8WUF5not detectable3
PRR16Q569H4not detectable3
PSCDBPO60759not detectable3
RAPGEF2Q9Y4G8not detectable3
RAPGEF6Q8TEU7not detectable3
RSBN1Q5VWQ0not detectable3
RTKNQ9BST9not detectable3
SAPCD1Q5SSQ6not detectable3
SBF1O95248not detectable3
SDC3O75056not detectable3
SDC4P31431not detectable3
SEMA4FO95754not detectable3
SHROOM4Q9ULL8not detectable3
SIPA1Q96FS4not detectable3
SLC16A1P53985not detectable3
SLC16A7O60669not detectable3
SLC1A3P43003not detectable3
SLC1A5Q15758not detectable3
SLCO1B1Q9Y6L6not detectable3
SLCO2B1O94956not detectable3
SMCHD1A6NHR9not detectable3
STK16O75716not detectable3
TAGAPQ8N103not detectable3
TECPR2O15040not detectable3
TGFAP01135not detectable3
TIAM1Q13009not detectable3
TMEM178BH3BS89not detectable3
TMEM215Q68D42not detectable3
TMEM225BP0DP42not detectable3
TNRC6AQ8NDV7not detectable3
TRMT13Q9NUP7not detectable3
TRPV3Q8NET8not detectable3
TUBB4BP68371not detectable3
TYRP1P17643not detectable3
UNC93AQ86WB7not detectable3
VANGL1Q8TAA9not detectable3
XKR7Q5GH72not detectable3
ZSCAN30Q86W11not detectable3
BIN1O00499not detectable3





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