You are looking at the quantitative interactomic profile of the molecule of HTRA4


UniProt ID: P83105
Molecule ID: HTRA4 (Link to all interactions of this molecule.)


The selection have 1 unique variants
non-modified profile

The selection have 1 unique fragments
368-476 fragment

The selection have 1 unique sites
PDZ sites

The current selection is unique





You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


Partners Experiment
IDUniProtModificationpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
ZNF831Q5JPB24.971
FAM71CQ8NEG04.961
PKN2Q165134.901
APBA1Q024104.891
BCRP112744.821
TTC24A2A3L64.771
GNG4P501504.761
ASIC3Q9UHC34.740.163
MARCHF4Q9P2E84.741
DCAF7P619624.681
AGMATQ9BSE54.662
YAP1P469374.651
GJC1P363834.641
KCNA7Q96RP84.611
WWTR1Q9GZV54.601
MCM7P339934.591
APCP250544.570.062
FAM167BQ9BTA04.551
PDLIM4P50479iso24.551
FCHSD2O948684.541
GJD4Q96KN94.511
MARCHF9Q86YJ54.501
LNX2Q8N4484.451
SORCS3Q9UPU34.441
NF2P352404.401
EPHB6O151974.391
KCNA6P176584.381
NPSR1Q6W5P44.381
MMP24Q9Y5R24.371
CACNA1DQ016684.361
EPHB3P547534.361
RNF146Q9NTX74.361
ATRNL1Q5VV634.331
FOXI1Q129514.291
FZD10Q9ULW24.291
DACT1Q9NYF04.261
FAT1Q145174.261
CLDN8P567484.231
PDZRN3Q9UPQ74.201
RGS12O149244.150.172
ADGRA3Q8IWK64.151
PRLHRP496834.151
SLC23A1Q9UHI74.151
CSPG4Q6UVK14.141
KCNJ1P480484.141
KIRREL1Q96J844.141
TRAF7Q6Q0C04.141
TRIM29Q141344.141
DENND5AQ6IQ264.131
CLDN18P568564.121
PRR16Q569H44.121
C3AR1Q165814.111
EPHA7Q153754.101
FAM110BQ8TC764.101
SLC6A3Q019594.101
CLDN2P577394.081
EVI5O604474.081
CTNND2Q9UQB34.061
PRKD2Q9BZL64.061
RASL11BQ9BPW54.061
JAM1Q9Y6244.051
NLGN4XQ8N0W44.041
CD226Q157624.011
PTPN18Q999524.011
GRIA3P422634.001
LNX1Q8TBB14.001
OR10G3Q8NGC44.001
SLC15A2Q163483.991
U2AF2P263683.991
CLDN4O144933.981
ERBB2P046263.981
PDGFRBP096193.981
PRKNO602603.981
UQCRC2P226953.981
CBPQ927933.97*2, detectable in 1
NLGN2Q8NFZ43.971
SLC45A4Q5BKX63.971
PTTG2Q9NZH53.961
SAPCD1Q5SSQ63.961
SLC34A1Q064953.961
CLDN14O955003.951
CRIPTQ9P0213.951
LPXNO607113.951
CACNG8Q8WXS53.941
FZD8Q9H4613.941
HDAC7Q8WUI43.941
MYOZ3Q8TDC03.941
TYRP1P176433.941
SCN4BQ8IWT13.931
ADGRA1Q86SQ63.921
CAPN6Q9Y6Q13.921
GRK6P432503.921
PPP1R3GB7ZBB83.921
TANC1Q9C0D53.921
VAC14Q08AM63.921
CIB2O758383.911
FLVCR1Q9Y5Y03.911
REELD1A0A1B0GV853.911
CBY2Q8NA613.901
CNKSR2Q8WXI23.901
NOS1APO750523.901
RRBP1Q9P2E93.901
SCN5AQ145243.901
SLC1A7O003413.901
SLC9A3P487643.901
SRCP129313.901
NET1Q7Z6283.89*4, detectable in 1
RALBP1Q153113.89*3, detectable in 1
CXCR1P250243.891
AQP6Q135203.881
KITP107213.881
ACE2Q9BYF13.87*2, detectable in 1
FAM110DQ8TAY73.871
KLHDC7AQ5VTJ33.871
HPV73-E6Q820053.86*2, detectable in 1
NECTIN3Q9NQS33.861
CTNNA1P352213.851
GRM5P415943.851
GUCY1A2P334023.851
PLCB2Q007223.851
SH2D3CQ8N5H73.851
SLCO1C1Q9NYB53.83*4, detectable in 1
OTULINQ96BN83.83*3, detectable in 1
PTPRGP234703.831
MTNR1AP480393.821
HTLV1-TAX1P034093.81*4, detectable in 2
RNF130Q86XS83.811
SLC22A3O757513.811
MKNK1Q9BUB53.801
MYOZ2Q9NPC63.801
STK16O757163.801
UNC93AQ86WB73.801
ABCC6O952553.791
AQP3Q924823.791
FZD1Q9UP383.791
JAM2P570873.791
HPV59-E6Q819643.78*2, detectable in 1
ADRA1DP251003.751
AMOTL1Q8IY633.751
TBC1D10AQ9BXI63.751
TRIM50Q86XT43.751
ARHGEF16Q5VV413.74*2, detectable in 1
DUSP10Q9Y6W63.741
GRIA2P422623.741
PLCB4Q151473.730.193
CTBP1Q133633.731
RPS6KA1Q15418(SEP)7323.72*5, detectable in 2
PTENP60484(ALY)4023.720.06*4, detectable in 3
RPS6KA1Q154183.71*6, detectable in 1
HTR2AP282233.711
ACOT6Q3I5F73.701
SSTR5P353463.701
MYOTQ9UBF93.691
NEBP209293.671
HPV49-L2P367623.661
BANF1O755313.641
MERS-EK9N5R33.630.05*4, detectable in 2
PTENP604843.62*4, detectable in 1
ADGRE5P489603.621
ADAM22Q9P0K13.611
ATP2B4P236343.60*3, detectable in 1
KIRREL2Q6UWL63.601
CYSLTR2Q9NS753.590.22*3, detectable in 2
GAS2L2Q8NHY33.591
TGFAP011353.591
DLL1O005483.531
TMEM215Q68D423.531
PLEKHG7Q6ZR373.501
EPHA6Q9UF333.491
EXOC4Q96A653.491
ATP2B1P200203.48*3, detectable in 2
ABRAXAS2Q150183.481
PKP4Q995693.481
RPS6KA1Q15418(TPO)7343.481
RASSF6Q6ZTQ33.46*2, detectable in 1
HPV16-E6P03126not detectable11
WNV-NS5Q9Q6P4not detectable6
HPV18-E6P06463not detectable5
ABCC4O15439not detectable4
HPV35-E6P27228not detectable4
SLC15A5A6NIM6not detectable4
ARHGEF26Q96DR7not detectable3
DGKZQ13574not detectable3
FRMPD4Q14CM0not detectable3
HBV-HbcP03146not detectable3
KCNA4P22459not detectable3
SARS-CoV2-EP0DTC4not detectable3
ABCA1O95477not detectable2
ARHGEF7Q14155not detectable2
CACNG4Q9UBN1not detectable2
CFTRP13569not detectable2
CTNNB1P35222not detectable2
DFNB31Q9P202not detectable2
DGKKQ5KSL6not detectable2
DOCK4Q8N1I0not detectable2
FAT3Q8TDW7not detectable2
FRMPD1Q5SYB0not detectable2
FZD7O75084not detectable2
GRASPQ7Z6J2not detectable2
HPV16-E6P03126(TPO)156not detectable2
HPV30-E6P36809not detectable2
HPV33-E6P06427not detectable2
HPV51-E6P26554not detectable2
HPV67-E6A4U7F2not detectable2
HPV82-E6Q9IR59not detectable2
KIR3DL3Q8N743not detectable2
MAP2K2P36507not detectable2
MAPK12P53778not detectable2
PBKQ96KB5not detectable2
SARS-Cov-EP59637not detectable2
SARS-Cov2-3aP0DTC3not detectable2
SARS-Cov2-NP0DTC9not detectable2
SLC2A1P11166not detectable2
TANC2Q9HCD6not detectable2
TJP2Q9UDY2not detectable2
ABCA2Q9BZC7not detectable1
ABCA7Q8IZY2not detectable1
ACOT8O14734not detectable1
ACTN2P35609not detectable1
ACVR2AP27037not detectable1
ADAM17P78536not detectable1
ADGRA2Q96PE1not detectable1
ADGRG1Q9Y653not detectable1
ADRB1P08588not detectable1
ADRB2P07550not detectable1
AKAP10O43572not detectable1
AKIP1Q9NQ31not detectable1
APPL1Q9UKG1not detectable1
ARAP3Q8WWN8not detectable1
ARHGAP17Q68EM7not detectable1
ARHGAP6O43182not detectable1
ARVCFO00192not detectable1
ASNSD1Q9NWL6not detectable1
ATP2A2P16615not detectable1
AXIN1O15169not detectable1
BAZ1AQ9NRL2not detectable1
BPIFA2Q96DR5not detectable1
CACNA1AO00555not detectable1
CACNG2Q9Y698not detectable1
CACYBPQ9HB71not detectable1
CAVIN3Q969G5not detectable1
CCDC134Q9H6E4not detectable1
CCL24O00175not detectable1
CCRL2O00421not detectable1
CD46P15529not detectable1
CDK18Q07002not detectable1
CES2O00748not detectable1
CES3Q6UWW8not detectable1
CGNQ9P2M7not detectable1
CITO14578not detectable1
CLDN1O95832not detectable1
CLDN10P78369not detectable1
CLDN19Q8N6F1not detectable1
CLDN20P56880not detectable1
CLDN3O15551not detectable1
CLDN7O95471not detectable1
CLDN9O95484not detectable1
CNTNAP2Q9UHC6not detectable1
CNTNAP4Q9C0A0not detectable1
COMMD3Q9UBI1not detectable1
CRB2Q5IJ48not detectable1
CRHR1P34998not detectable1
CTNNA2P26232not detectable1
DCHS2Q6V1P9not detectable1
DGKHQ86XP1not detectable1
DGKIO75912not detectable1
DLGAP4Q9Y2H0not detectable1
DUSP5Q16690not detectable1
EFNB1P52799not detectable1
EFNB3Q15768not detectable1
EGLN1Q9GZT9not detectable1
ERBB4Q15303not detectable1
EZH1Q92800not detectable1
FKBP4Q02790not detectable1
FMNL3Q8IVF7not detectable1
FZD2Q14332not detectable1
FZD4Q9ULV1not detectable1
GAB3Q8WWW8not detectable1
GAGE12JA6NER3not detectable1
GDAQ9Y2T3not detectable1
GHRHRQ02643not detectable1
GJA1P17302not detectable1
GJD2Q9UKL4not detectable1
GLAP06280not detectable1
GOLT1AQ6ZVE7not detectable1
GOT1L1Q8NHS2not detectable1
GPR12P47775not detectable1
GPR6P46095not detectable1
GPRC6AQ5T6X5not detectable1
GRID2O43424not detectable1
GRIK2Q13002not detectable1
GRIN1Q05586not detectable1
GRIN2AQ12879not detectable1
GRIN2BQ13224not detectable1
GRIN2CQ14957not detectable1
GRIP1Q9Y3R0not detectable1
GYPCP04921not detectable1
HCN2Q9UL51not detectable1
HNRNPKP61978not detectable1
HPV18-E6P06463(TPO)156not detectable1
HPV31-E6P17386not detectable1
HPV33-E6P06427(TPO)147not detectable1
HPV35-E6P27228(TPO)147not detectable1
HSPA5P11021not detectable1
HTR2CP28335not detectable1
IGF1RP08069not detectable1
IGSF5Q9NSI5not detectable1
IQSEC2Q5JU85not detectable1
ITKQ08881not detectable1
JAG1P78504not detectable1
JAM3Q9BX67not detectable1
JUPP14923not detectable1
KARS1Q15046not detectable1
KCNA1Q09470not detectable1
KCNA5P22460not detectable1
KCNB1Q14721not detectable1
KCNJ12Q14500not detectable1
KCNJ18B7U540not detectable1
KCNJ4P48050not detectable1
KCNJ9Q92806not detectable1
KCNT1Q5JUK3not detectable1
KCNT2Q6UVM3not detectable1
KCNV1Q6PIU1not detectable1
KCTD3Q9Y597not detectable1
KIDINS220Q9ULH0not detectable1
KIF17Q9P2E2not detectable1
LPAR1Q92633not detectable1
LRP4O75096not detectable1
LRRC4Q9HBW1not detectable1
LRRC4BQ9NT99not detectable1
LSM14AQ8ND56not detectable1
MAP4P27816not detectable1
MAP7D2Q96T17not detectable1
MARCHF3Q86UD3not detectable1
MAS1P04201not detectable1
MCCP23508not detectable1
MLLT4P55196not detectable1
MTMR1Q13613not detectable1
MUC3AQ02505not detectable1
MUC3BQ9H195not detectable1
MYO18AQ92614not detectable1
MYOZ1Q9NP98not detectable1
MYPNQ86TC9not detectable1
NCBP2LA6PVI3not detectable1
NCF1P14598not detectable1
NDE1Q9NXR1not detectable1
NECTIN1Q15223not detectable1
NHERF1O14745not detectable1
NHERF2Q15599not detectable1
NHERF3Q5T2W1not detectable1
NOSTRINQ8IVI9not detectable1
NRXN1Q9ULB1not detectable1
NRXN3Q9Y4C0rs746444206not detectable1
NRXN3Q9HDB5not detectable1
OR8G1Q15617not detectable1
PALLSQ8WX93not detectable1
PDLIM2Q96JY6not detectable1
PDLIM4P50479not detectable1
PDLIM7Q9NR12not detectable1
PDZRN4Q6ZMN7not detectable1
PFKMP08237not detectable1
PLCB1Q9NQ66not detectable1
PLEKHA1Q9HB21not detectable1
PLEKHA2Q9HB19not detectable1
PLEKHH2Q8IVE3not detectable1
PLXNB1O43157not detectable1
PODXLO00592not detectable1
POLR1DP0DPB6not detectable1
PPFIA1Q13136not detectable1
PPP1R13LQ8WUF5not detectable1
PRKACAP17612not detectable1
PRKCAP17252not detectable1
PSCDBPO60759not detectable1
PTGIRP43119not detectable1
PTH1RQ03431not detectable1
PTH2RP49190not detectable1
PTPRZ1P23471not detectable1
RAB9AP51151not detectable1
RAMP3O60896not detectable1
RAPGEF2Q9Y4G8not detectable1
RAPGEF6Q8TEU7not detectable1
RCN1Q15293not detectable1
RCN2Q14257not detectable1
RPS6KA1Q15418(TPO)733not detectable1
RPS6KA3P51812not detectable1
RSBN1Q5VWQ0not detectable1
RSRC2Q7L4I2not detectable1
RTKNQ9BST9not detectable1
SBF1O95248not detectable1
SCN4AP35499not detectable1
SCN8AQ9UQD0not detectable1
SDC2P34741not detectable1
SDC3O75056not detectable1
SDC4P31431not detectable1
SDK2Q58EX2not detectable1
SEMA4CQ9C0C4not detectable1
SEMA4FO95754not detectable1
SHKBP1Q8TBC3not detectable1
SHROOM3Q8TF72not detectable1
SHROOM4Q9ULL8not detectable1
SIPA1Q96FS4not detectable1
SLC16A1P53985not detectable1
SLC16A3O15427not detectable1
SLC16A7O60669not detectable1
SLC17A1Q14916not detectable1
SLC1A1P43005not detectable1
SLC1A3P43003not detectable1
SLC1A4P43007not detectable1
SLC1A5Q15758not detectable1
SLC22A11Q9NSA0not detectable1
SLC22A12Q96S37not detectable1
SLC22A9Q8IVM8not detectable1
SLC26A3P40879not detectable1
SLC2A3P11169not detectable1
SLC2A7Q6PXP3not detectable1
SLC4A7Q9Y6M7not detectable1
SLC5A12Q1EHB4not detectable1
SLCO1A2P46721not detectable1
SLCO1B1Q9Y6L6not detectable1
SLCO2B1O94956not detectable1
SMCHD1A6NHR9not detectable1
TAGAPQ8N103not detectable1
TBPL1P62380not detectable1
TECPR2O15040not detectable1
TIAM1Q13009not detectable1
TJP3O95049not detectable1
TMEM151BQ8IW70not detectable1
TMEM178AQ8NBL3not detectable1
TMEM178BH3BS89not detectable1
TMEM225BP0DP42not detectable1
TMIGD1Q6UXZ0not detectable1
TNRC6AQ8NDV7not detectable1
TNRC6BQ9UPQ9not detectable1
TRAF2Q12933not detectable1
TRIP6Q15654not detectable1
TRMT13Q9NUP7not detectable1
TRPC5Q9UL62not detectable1
TRPM1Q7Z4N2not detectable1
TRPV3Q8NET8not detectable1
TRPV6Q9H1D0not detectable1
TUBB4BP68371not detectable1
TYRO3Q06418not detectable1
USH1CQ9Y6N9not detectable1
VANGL1Q8TAA9not detectable1
XKR7Q5GH72not detectable1
ZNF599Q96NL3not detectable1
ZSCAN30Q86W11not detectable1





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