You are looking at the quantitative interactomic profile of the molecule of DLG4


UniProt ID: P78352
Molecule ID: DLG4 (Link to all interactions of this molecule.)
Alternative name(s): PSD95


The selection have 1 unique variants
non-modified profile

The selection have 3 unique fragments
155-249 fragment
306-403 fragment
62-152 fragment

The selection have 3 unique sites
PDZ_1 sites
PDZ_2 sites
PDZ_3 sites







You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


Partners Experiment
IDUniProtModificationpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
CYSLTR2Q9NS755.640.5516
MARCHF3Q86UD35.480.453
HPV18-E6P064635.410.29*23, detectable in 22
EVI5O604475.370.653
FRMPD4Q14CM05.360.3217
HTLV1-TAX1P034095.330.1919
HPV35-E6P272285.200.2120
EXOC4Q96A655.200.553
NET1Q7Z6285.190.4320
ADGRA3Q8IWK65.190.203
HPV31-E6P173865.150.138
HPV33-E6P064275.100.3114
MARCHF4Q9P2E85.060.173
PBKQ96KB55.040.34*10, detectable in 5
MARCHF9Q86YJ55.040.193
SCN4AP354995.030.543
GRIN2AQ128795.000.29*3, detectable in 2
ZNF599Q96NL35.000.513
KCNA4P224594.990.31*6, detectable in 4
HPV16-E6P031264.980.2239
FAM110DQ8TAY74.960.503
XKR7Q5GH724.920.01*3, detectable in 2
HPV51-E6P265544.890.1410
CRIPTQ9P0214.890.423
RASL11BQ9BPW54.890.183
ADGRA1Q86SQ64.890.213
ADGRA2Q96PE14.880.313
DUSP10Q9Y6W64.880.633
PTPRZ1P234714.870.22*3, detectable in 2
DACT1Q9NYF04.830.413
TTC24A2A3L64.830.12*3, detectable in 2
PTPRGP234704.800.21*3, detectable in 2
DGKIO759124.790.18*3, detectable in 2
TGFAP011354.790.04*3, detectable in 2
ATP2B4P236344.790.26*13, detectable in 12
HPV30-E6P368094.780.5110
RASSF6Q6ZTQ34.770.4010
IQSEC2Q5JU854.770.463
HPV59-E6Q819644.750.4614
CACNG4Q9UBN14.750.176
CACNG8Q8WXS54.740.253
MCM7P339934.740.323
PRR16Q569H44.700.443
RALBP1Q153114.690.37*13, detectable in 12
CACNG2Q9Y6984.690.163
ERBB4Q153034.690.333
CCRL2O004214.680.02*3, detectable in 2
TANC1Q9C0D54.680.313
FZD2Q143324.670.303
APCP250544.660.267
CRHR1P349984.640.213
KCNA7Q96RP84.640.393
AGMATQ9BSE54.610.434
GRIN2BQ132244.610.25*4, detectable in 2
FAT1Q145174.610.19*3, detectable in 2
HPV82-E6Q9IR594.590.1914
HBV-HbcP031464.590.199
GRIN2CQ149574.590.643
SCN5AQ145244.590.14*3, detectable in 2
ZSCAN30Q86W114.580.303
SLC1A7O003414.550.11*3, detectable in 2
HPV67-E6A4U7F24.550.27*10, detectable in 8
CTNND2Q9UQB34.540.18*3, detectable in 2
ARHGEF16Q5VV414.540.70*10, detectable in 8
VANGL1Q8TAA94.530.114
SAPCD1Q5SSQ64.530.053
FZD4Q9ULV14.520.523
ARVCFO001924.510.30*4, detectable in 2
FAT3Q8TDW74.470.10*4, detectable in 2
FZD1Q9UP384.470.513
TMEM178AQ8NBL34.470.14*3, detectable in 2
MTMR1Q136134.460.24*4, detectable in 2
TANC2Q9HCD64.460.14*4, detectable in 2
GUCY1A2P334024.460.343
LRRC4Q9HBW14.460.243
SLC45A4Q5BKX64.460.13*3, detectable in 2
KIRREL1Q96J844.450.133
PKP4Q995694.440.18*3, detectable in 2
LRP4O750964.430.26*4, detectable in 2
ABCA1O954774.420.607
ARHGEF26Q96DR74.410.507
BCRP112744.390.503
RNF146Q9NTX74.390.663
GOLT1AQ6ZVE74.380.34*3, detectable in 2
SDK2Q58EX24.370.12*3, detectable in 2
SLCO1C1Q9NYB54.370.25*21, detectable in 20
ADAM17P785364.360.043
GAS2L2Q8NHY34.360.33*3, detectable in 2
KCNJ12Q145004.350.124
NCBP2LA6PVI34.350.213
IGSF5Q9NSI54.320.17*3, detectable in 2
TRPV3Q8NET84.320.093
FAM110BQ8TC764.300.23*3, detectable in 2
RTKNQ9BST94.290.074
HTR2CP283354.290.35*3, detectable in 2
LRRC4BQ9NT994.290.27*3, detectable in 2
FAM167BQ9BTA04.280.113
HPV73-E6Q820054.270.27*10, detectable in 5
DGKZQ135744.260.49*17, detectable in 16
C3AR1Q165814.260.513
FZD7O750844.240.22*10, detectable in 9
MAPK12P537784.220.21*7, detectable in 6
CNKSR2Q8WXI24.220.524
MAS1P042014.220.24*4, detectable in 2
TMEM151BQ8IW704.220.263
ADRA1DP251004.220.33*3, detectable in 2
BPIFA2Q96DR54.220.363
FOXI1Q129514.220.463
HTR2AP282234.220.52*3, detectable in 2
PTENP60484(ALY)4024.210.30*16, detectable in 7
ATRNL1Q5VV634.210.243
GRIN1Q055864.200.10*4, detectable in 2
RGS12O149244.190.05*7, detectable in 4
DLL1O005484.160.23*4, detectable in 2
MUC3AQ025054.16*3, detectable in 1
PRKCAP172524.160.283
PTPN18Q999524.160.10*3, detectable in 2
TMEM215Q68D424.150.514
KCNA5P224604.140.30*7, detectable in 2
KCNJ4P480504.140.03*3, detectable in 2
KIRREL2Q6UWL64.140.253
KIR3DL3Q8N7434.130.09*7, detectable in 2
GDAQ9Y2T34.130.29*4, detectable in 2
ADRB1P085884.130.09*3, detectable in 2
MAP2K2P365074.12*7, detectable in 1
ADAM22Q9P0K14.110.143
SEMA4CQ9C0C44.110.12*3, detectable in 2
GJD4Q96KN94.11*3, detectable in 1
SLC16A7O606694.11*3, detectable in 1
SLC2A7Q6PXP34.11*3, detectable in 1
SLC15A5A6NIM64.110.16*21, detectable in 11
ATP2B1P200204.090.167
NCF1P145984.090.42*3, detectable in 2
KCNB1Q147214.09*3, detectable in 1
ABCC4O154394.090.23*18, detectable in 17
WNV-NS5Q9Q6P44.080.26*10, detectable in 3
SORCS3Q9UPU34.080.263
SCN8AQ9UQD04.060.54*3, detectable in 2
FZD10Q9ULW24.060.05*3, detectable in 2
GNG4P501504.060.093
PLCB4Q151474.050.12*7, detectable in 6
HPV49-L2P367624.050.30*4, detectable in 3
FCHSD2O948684.050.16*3, detectable in 2
PLEKHA2Q9HB194.040.34*3, detectable in 2
SLC23A1Q9UHI74.030.13*3, detectable in 2
MMP24Q9Y5R24.03*3, detectable in 1
OTULINQ96BN84.020.197
CACNA1DQ016684.02*3, detectable in 1
KARS1Q150464.020.333
KCNA1Q094704.010.373
LPAR1Q926334.01*3, detectable in 1
RRBP1Q9P2E94.010.273
SLC2A3P111694.010.233
TYRP1P176434.010.10*3, detectable in 2
SLC16A3O154274.000.124
CD46P155294.000.30*3, detectable in 2
RAMP3O608964.000.02*3, detectable in 2
CES2O007484.00*3, detectable in 1
LNX2Q8N4483.990.414
PDZRN3Q9UPQ73.990.16*4, detectable in 2
MUC3BQ9H1953.980.16*3, detectable in 2
SMCHD1A6NHR93.980.17*3, detectable in 2
COMMD3Q9UBI13.97*3, detectable in 1
RPS6KA3P518123.940.183
PLXNB1O431573.940.26*3, detectable in 2
SLC17A1Q149163.930.11*3, detectable in 2
PFKMP082373.93*3, detectable in 1
GPR12P477753.92*3, detectable in 1
GAB3Q8WWW83.910.12*3, detectable in 2
TRIP6Q156543.91*3, detectable in 1
MCCP235083.890.06*3, detectable in 2
TIAM1Q130093.88*4, detectable in 1
DGKHQ86XP13.880.03*3, detectable in 2
ARHGAP6O431823.870.42*7, detectable in 4
KCNA6P176583.870.253
SLCO2B1O949563.870.04*3, detectable in 2
STK16O757163.87*3, detectable in 1
TAGAPQ8N1033.850.354
SLC1A4P430073.850.06*3, detectable in 2
BAZ1AQ9NRL23.85*3, detectable in 1
NLGN4XQ8N0W43.840.233
OR8G1Q156173.840.03*3, detectable in 2
NLGN2Q8NFZ43.840.02*3, detectable in 2
FLVCR1Q9Y5Y03.84*3, detectable in 1
RAPGEF6Q8TEU73.830.22*4, detectable in 2
TMEM225BP0DP423.820.23*3, detectable in 2
PLEKHH2Q8IVE33.810.10*3, detectable in 2
TRPM1Q7Z4N23.810.113
NECTIN3Q9NQS33.790.04*3, detectable in 2
CLDN8P567483.79*3, detectable in 1
RPS6KA1Q15418(SEP)7323.790.13*20, detectable in 6
ASIC3Q9UHC33.790.17*13, detectable in 10
ACOT6Q3I5F73.780.10*3, detectable in 2
SLC15A2Q163483.780.09*3, detectable in 2
JAG1P785043.78*3, detectable in 1
CBPQ927933.780.24*10, detectable in 2
RAPGEF2Q9Y4G83.770.18*4, detectable in 2
RSBN1Q5VWQ03.770.133
TMIGD1Q6UXZ03.760.02*7, detectable in 4
IGF1RP080693.76*3, detectable in 1
GPR6P460953.75*4, detectable in 1
GRASPQ7Z6J23.740.07*7, detectable in 4
EPHA7Q153753.740.01*3, detectable in 2
SLC2A1P111663.730.22*8, detectable in 4
MAP4P278163.730.264
RCN1Q152933.730.193
GRIA2P422623.73*3, detectable in 1
NECTIN1Q152233.73*3, detectable in 1
CDK18Q070023.720.03*3, detectable in 2
LSM14AQ8ND563.71*3, detectable in 1
ITKQ088813.700.08*3, detectable in 2
ABCA7Q8IZY23.70*3, detectable in 1
DOCK4Q8N1I03.69*7, detectable in 2
OR10G3Q8NGC43.690.20*3, detectable in 2
FZD8Q9H4613.69*3, detectable in 1
FRMPD1Q5SYB03.680.13*7, detectable in 5
TJP2Q9UDY23.680.16*7, detectable in 2
MERS-EK9N5R33.680.09*13, detectable in 6
GAGE12JA6NER33.670.08*3, detectable in 2
CD226Q157623.670.123
TRIM29Q141343.670.12*3, detectable in 2
KCNJ9Q928063.67*3, detectable in 1
NRXN3Q9HDB53.67*3, detectable in 1
SEMA4FO957543.67*3, detectable in 1
PTENP604843.670.14*16, detectable in 8
RPS6KA1Q15418(TPO)7343.660.17*7, detectable in 4
EPHB3P547533.66*3, detectable in 1
KCNJ18B7U5403.66*3, detectable in 1
SLC26A3P408793.66*3, detectable in 1
RPS6KA1Q154183.660.07*22, detectable in 6
ACVR2AP270373.650.14*7, detectable in 6
ABCA2Q9BZC73.650.05*3, detectable in 2
GJD2Q9UKL43.65*3, detectable in 1
SLC4A7Q9Y6M73.640.06*4, detectable in 3
CCL24O001753.64*3, detectable in 1
NF2P352403.640.113
TRAF7Q6Q0C03.630.07*3, detectable in 2
CLDN3O155513.63*3, detectable in 1
GHRHRQ026433.63*3, detectable in 1
KCNT2Q6UVM33.62*7, detectable in 4
CITO145783.62*4, detectable in 2
CLDN18P568563.620.06*3, detectable in 2
U2AF2P263683.62*3, detectable in 1
KLHDC7AQ5VTJ33.610.11*3, detectable in 2
SLC22A11Q9NSA03.610.03*3, detectable in 2
EPHB6O151973.610.11*3, detectable in 2
ACTN2P356093.61*3, detectable in 1
GYPCP049213.61*3, detectable in 1
ABRAXAS2Q150183.600.05*4, detectable in 2
TJP3O950493.600.07*4, detectable in 2
PDGFRBP096193.600.12*3, detectable in 2
AKIP1Q9NQ313.60*3, detectable in 1
CLDN1O958323.60*3, detectable in 1
ADGRG1Q9Y6533.60*3, detectable in 1
GLAP062803.590.05*3, detectable in 2
FKBP4Q027903.59*3, detectable in 1
KCNJ1P480483.59*3, detectable in 1
CBY2Q8NA613.580.08*3, detectable in 2
HPV18-E6P06463(TPO)1563.580.07*3, detectable in 2
SLC1A5Q157583.56*4, detectable in 1
KCNT1Q5JUK33.560.03*3, detectable in 2
HPV35-E6P27228(TPO)1473.56*3, detectable in 1
NRXN3Q9Y4C0rs7464442063.56*3, detectable in 1
SLC22A3O757513.55*3, detectable in 1
ABCC6O952553.55*3, detectable in 1
PDZRN4Q6ZMN73.540.02*4, detectable in 3
PPP1R13LQ8WUF53.54*4, detectable in 1
MAP7D2Q96T173.540.06*3, detectable in 2
CLDN2P577393.540.03*3, detectable in 2
CLDN4O144933.54*3, detectable in 1
ASNSD1Q9NWL63.54*3, detectable in 1
EFNB3Q157683.54*3, detectable in 1
SIPA1Q96FS43.54*3, detectable in 1
RCN2Q142573.53*3, detectable in 2
MYOTQ9UBF93.53*3, detectable in 1
CLDN10P783693.52*3, detectable in 1
WWTR1Q9GZV53.510.03*3, detectable in 2
PLCB1Q9NQ663.51*3, detectable in 1
PTH2RP491903.51*3, detectable in 1
SLC34A1Q064953.51*3, detectable in 1
GJC1P363833.51*3, detectable in 1
RNF130Q86XS83.51*3, detectable in 1
ACE2Q9BYF13.50*7, detectable in 1
SLC16A1P539853.50*4, detectable in 1
CIB2O758383.50*3, detectable in 1
HSPA5P110213.50*3, detectable in 1
KIDINS220Q9ULH03.50*3, detectable in 1
MKNK1Q9BUB53.50*3, detectable in 1
NOSTRINQ8IVI93.50*3, detectable in 1
TMEM178BH3BS893.50*3, detectable in 1
TNRC6BQ9UPQ93.50*3, detectable in 1
PDLIM7Q9NR123.49*4, detectable in 1
RSRC2Q7L4I23.49*3, detectable in 1
SLC1A3P430033.49*3, detectable in 1
NPSR1Q6W5P43.49*3, detectable in 1
ERBB2P046263.48*3, detectable in 1
PRKD2Q9BZL63.48*3, detectable in 1
JAM1Q9Y6243.47*3, detectable in 1
ARHGEF7Q14155not detectable8
HPV16-E6P03126(TPO)156not detectable8
SARS-CoV2-EP0DTC4not detectable8
RPS6KA1Q15418(TPO)733not detectable7
CFTRP13569not detectable7
DGKKQ5KSL6not detectable7
SARS-Cov-EP59637not detectable6
SARS-Cov2-NP0DTC9not detectable6
DFNB31Q9P202not detectable6
SARS-Cov2-3aP0DTC3not detectable5
ADRB2P07550not detectable4
ARHGAP17Q68EM7not detectable4
CACYBPQ9HB71not detectable4
CGNQ9P2M7not detectable4
CNTNAP4Q9C0A0not detectable4
CTNNB1P35222not detectable4
DLGAP4Q9Y2H0not detectable4
KCTD3Q9Y597not detectable4
LNX1Q8TBB1not detectable4
MYO18AQ92614not detectable4
NHERF1O14745not detectable4
NHERF2Q15599not detectable4
NHERF3Q5T2W1not detectable4
NRXN1Q9ULB1not detectable4
PDLIM2Q96JY6not detectable4
PDLIM4P50479not detectable4
PODXLO00592not detectable4
PSCDBPO60759not detectable4
SHKBP1Q8TBC3not detectable4
SHROOM3Q8TF72not detectable4
SHROOM4Q9ULL8not detectable4
USH1CQ9Y6N9not detectable4
ACOT8O14734not detectable3
ADGRE5P48960not detectable3
AKAP10O43572not detectable3
AMOTL1Q8IY63not detectable3
APBA1Q02410not detectable3
APPL1Q9UKG1not detectable3
AQP3Q92482not detectable3
AQP6Q13520not detectable3
ARAP3Q8WWN8not detectable3
ATP2A2P16615not detectable3
AXIN1O15169not detectable3
BANF1O75531not detectable3
CACNA1AO00555not detectable3
CAPN6Q9Y6Q1not detectable3
CAVIN3Q969G5not detectable3
CCDC134Q9H6E4not detectable3
CES3Q6UWW8not detectable3
CLDN14O95500not detectable3
CLDN19Q8N6F1not detectable3
CLDN20P56880not detectable3
CLDN7O95471not detectable3
CLDN9O95484not detectable3
CNTNAP2Q9UHC6not detectable3
CRB2Q5IJ48not detectable3
CSPG4Q6UVK1not detectable3
CTBP1Q13363not detectable3
CTNNA1P35221not detectable3
CTNNA2P26232not detectable3
CXCR1P25024not detectable3
DCAF7P61962not detectable3
DCHS2Q6V1P9not detectable3
DENND5AQ6IQ26not detectable3
DUSP5Q16690not detectable3
EFNB1P52799not detectable3
EGLN1Q9GZT9not detectable3
EPHA6Q9UF33not detectable3
EZH1Q92800not detectable3
FAM71CQ8NEG0not detectable3
FMNL3Q8IVF7not detectable3
GJA1P17302not detectable3
GOT1L1Q8NHS2not detectable3
GPRC6AQ5T6X5not detectable3
GRIA3P42263not detectable3
GRID2O43424not detectable3
GRIK2Q13002not detectable3
GRIP1Q9Y3R0not detectable3
GRK6P43250not detectable3
GRM5P41594not detectable3
HCN2Q9UL51not detectable3
HDAC7Q8WUI4not detectable3
HNRNPKP61978not detectable3
HPV33-E6P06427(TPO)147not detectable3
JAM2P57087not detectable3
JAM3Q9BX67not detectable3
JUPP14923not detectable3
KCNV1Q6PIU1not detectable3
KIF17Q9P2E2not detectable3
KITP10721not detectable3
LPXNO60711not detectable3
MLLT4P55196not detectable3
MTNR1AP48039not detectable3
MYOZ1Q9NP98not detectable3
MYOZ2Q9NPC6not detectable3
MYOZ3Q8TDC0not detectable3
MYPNQ86TC9not detectable3
NDE1Q9NXR1not detectable3
NEBP20929not detectable3
NOS1APO75052not detectable3
PALLSQ8WX93not detectable3
PDLIM4P50479iso2not detectable3
PKN2Q16513not detectable3
PLCB2Q00722not detectable3
PLEKHA1Q9HB21not detectable3
PLEKHG7Q6ZR37not detectable3
POLR1DP0DPB6not detectable3
PPFIA1Q13136not detectable3
PPP1R3GB7ZBB8not detectable3
PRKACAP17612not detectable3
PRKNO60260not detectable3
PRLHRP49683not detectable3
PTGIRP43119not detectable3
PTH1RQ03431not detectable3
PTTG2Q9NZH5not detectable3
RAB9AP51151not detectable3
REELD1A0A1B0GV85not detectable3
SBF1O95248not detectable3
SCN4BQ8IWT1not detectable3
SDC2P34741not detectable3
SDC3O75056not detectable3
SDC4P31431not detectable3
SH2D3CQ8N5H7not detectable3
SLC1A1P43005not detectable3
SLC22A12Q96S37not detectable3
SLC22A9Q8IVM8not detectable3
SLC5A12Q1EHB4not detectable3
SLC6A3Q01959not detectable3
SLC9A3P48764not detectable3
SLCO1A2P46721not detectable3
SLCO1B1Q9Y6L6not detectable3
SRCP12931not detectable3
SSTR5P35346not detectable3
TBC1D10AQ9BXI6not detectable3
TBPL1P62380not detectable3
TECPR2O15040not detectable3
TNRC6AQ8NDV7not detectable3
TRAF2Q12933not detectable3
TRIM50Q86XT4not detectable3
TRMT13Q9NUP7not detectable3
TRPC5Q9UL62not detectable3
TRPV6Q9H1D0not detectable3
TUBB4BP68371not detectable3
TYRO3Q06418not detectable3
UNC93AQ86WB7not detectable3
UQCRC2P22695not detectable3
VAC14Q08AM6not detectable3
YAP1P46937not detectable3
ZNF831Q5JPB2not detectable3





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