You are looking at the quantitative interactomic profile of the molecule of PTEN


UniProt ID: P60484
Molecule ID: PTEN (Link to all interactions of this molecule.)
Alternative name(s): MMAC1 TEP1


The selection have 2 unique variants
non-modified profile
(ALY)402 modified profile

The selection have 3 unique fragments
391-403 fragment
393-403 fragment
394-403 fragment

The selection have 1 unique sites
PBM sites







You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


SelectionPartners Experiment
ModificationIDUniProtpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
(ALY)402PDZD7Q9H5P45.660.13*8, detectable in 7
(ALY)402MAST2Q6P0Q85.520.188
MAST2Q6P0Q85.440.287
(ALY)402SNX27Q96L925.350.068
(ALY)402GRASPQ7Z6J25.330.164
(ALY)402HTRA1Q927435.010.058
SNX27Q96L925.000.186
(ALY)402LNX2Q8N4484.980.06*9, detectable in 4
(ALY)402PTPN13Q129234.96*8, detectable in 1
PDZD7Q9H5P44.930.28*11, detectable in 7
(ALY)402MAST1Q9Y2H94.870.247
(ALY)402NHERF1O147454.85*2, detectable in 1
MAST1Q9Y2H94.810.206
(ALY)402ARHGEF11O150854.800.264
(ALY)402SNTB1Q138844.770.087
GRASPQ7Z6J24.750.194
(ALY)402RADILQ96JH84.680.044
(ALY)402FRMPD2Q68DX34.630.05*12, detectable in 4
(ALY)402RHPN1Q8TCX54.610.083
MAGI1Q96QZ74.600.23*18, detectable in 4
RHPN1Q8TCX54.530.183
(ALY)402SNTA1Q134244.480.157
(ALY)402GRID2IPA4D2P64.440.02*10, detectable in 6
(ALY)402DLG3Q927964.420.39*12, detectable in 5
(ALY)402ARHGEF12Q9NZN54.370.177
(ALY)402SNTG1Q9NSN84.360.064
(ALY)402MAGI3Q5TCQ94.350.24*8, detectable in 6
(ALY)402MAGI2Q86UL84.340.41*25, detectable in 23
MAGI3Q5TCQ94.330.26*14, detectable in 3
HTRA1Q927434.320.037
RGS3P497964.321
(ALY)402APBA1Q024104.310.04*7, detectable in 3
(ALY)402GOPCQ9HD264.270.137
(ALY)402PTPN3P260454.270.13*5, detectable in 4
PARD6BQ9BYG54.25*2, detectable in 1
LNX2Q8N4484.240.21*12, detectable in 3
PDZRN3Q9UPQ74.23*7, detectable in 1
(ALY)402DLG1Q129594.230.36*12, detectable in 9
SHANK1Q9Y5664.220.173
(ALY)402PDZD2O150184.210.17*9, detectable in 4
NHERF1O147454.210.25*3, detectable in 2
(ALY)402DLG4P783524.210.30*16, detectable in 7
FRMPD2Q68DX34.210.10*12, detectable in 4
(ALY)402GORASP2Q9H8Y84.200.144
ARHGEF11O150854.190.21*4, detectable in 3
SNTB2Q134254.19*2, detectable in 1
PTPN13Q129234.180.46*10, detectable in 4
(ALY)402MAGI1Q96QZ74.170.61*14, detectable in 5
(ALY)402DLG2Q157004.160.28*8, detectable in 7
NHERF2Q155994.160.23*6, detectable in 5
TJP2Q9UDY24.14*6, detectable in 1
MAGI2Q86UL84.140.31*25, detectable in 14
(ALY)402MPDZO759704.140.32*22, detectable in 10
SNTB1Q138844.120.178
ARHGEF12Q9NZN54.090.137
(ALY)402InaDlQ8NI354.080.41*36, detectable in 19
GRID2IPA4D2P64.080.06*10, detectable in 5
(ALY)402SHANK1Q9Y5664.070.164
(ALY)402NHERF3Q5T2W14.060.28*16, detectable in 5
GOPCQ9HD264.060.177
(ALY)402MAST3O603074.061
APBA1Q024104.050.06*6, detectable in 3
LNX1Q8TBB14.050.50*12, detectable in 5
LIMK2P536714.04*4, detectable in 1
(ALY)402SHANK3Q9BYB04.041
(ALY)402DFNB31Q9P2024.020.30*12, detectable in 7
(ALY)402TIAM2Q8IVF54.00*4, detectable in 1
GORASP2Q9H8Y83.990.22*4, detectable in 3
PDLIM3Q53GG53.99*2, detectable in 1
MPDZO759703.970.40*29, detectable in 9
(ALY)402GORASP1Q9BQQ33.970.144
(ALY)402SHANK2Q9UPX83.971
TJP1Q071573.960.38*9, detectable in 2
PTPN3P260453.960.02*5, detectable in 3
InadlQ8NI353.960.36*39, detectable in 10
(ALY)402TJP1Q071573.94*9, detectable in 1
(ALY)402SCRIBQ141603.930.41*20, detectable in 12
LAP2Q96RT13.930.145
SNTG1Q9NSN83.930.10*4, detectable in 3
SCRIBQ141603.930.41*21, detectable in 7
(ALY)402LAP2Q96RT13.920.066
RADILQ96JH83.920.01*3, detectable in 2
(ALY)402LIN7CQ9NUP93.91*5, detectable in 1
SNTG2Q9NY993.900.19*8, detectable in 3
NHERF4Q86UT53.900.29*14, detectable in 3
(ALY)402LNX1Q8TBB13.880.23*11, detectable in 6
(ALY)402PARD3Q8TEW03.870.18*6, detectable in 3
SNTA1Q134243.860.157
DFNB31Q9P2023.850.22*12, detectable in 7
DLG1Q129593.800.19*12, detectable in 6
PARD3BQ8TEW83.800.12*12, detectable in 3
(ALY)402TX1BP3O149073.800.065
PARD3Q8TEW03.780.23*7, detectable in 2
PDZD2O150183.780.23*13, detectable in 5
ARHGAP21Q5T5U33.77*4, detectable in 1
PICK1Q9NRD53.77*3, detectable in 1
NHERF3Q5T2W13.770.22*17, detectable in 8
DLG3Q927963.770.16*12, detectable in 4
MYO18AQ926143.771
(ALY)402PICK1Q9NRD53.75*4, detectable in 1
(ALY)402TJP2Q9UDY23.740.14*6, detectable in 4
(ALY)402NHERF2Q155993.740.03*5, detectable in 2
(ALY)402HTRA4P831053.720.06*4, detectable in 3
(ALY)402NHERF4Q86UT53.720.10*13, detectable in 2
(ALY)402NOS1P294753.710.074
GORASP1Q9BQQ33.710.17*4, detectable in 2
(ALY)402LIN7BQ9HAP63.670.10*4, detectable in 2
DLG4P783523.670.14*16, detectable in 8
(ALY)402IL16Q140053.660.12*13, detectable in 4
(ALY)402CNKSR1Q969H43.661
SYNJ2BPP571053.65*8, detectable in 2
DLG2Q157003.630.09*9, detectable in 3
HTRA4P831053.62*4, detectable in 1
GRIP1Q9Y3R03.620.10*24, detectable in 2
PDZRN4Q6ZMN73.62*10, detectable in 2
(ALY)402SYNJ2BPP571053.61*9, detectable in 2
(ALY)402SNTG2Q9NY993.610.16*8, detectable in 7
(ALY)402MPP6Q9NZW53.59*4, detectable in 1
MAST3O603073.59*2, detectable in 1
PPP1R9BQ96SB33.54*2, detectable in 1
GIPC2Q8TF653.53*4, detectable in 2
GRIP2Q9C0E43.530.03*22, detectable in 3
SHANK3Q9BYB03.521
IL16Q140053.51*14, detectable in 2
TX1BP3O149073.49*4, detectable in 1
LIN7BQ9HAP63.49*4, detectable in 1
CASKO149363.47*4, detectable in 1
(ALY)402GRIP1Q9Y3R0not detectable21
(ALY)402GRIP2Q9C0E4not detectable20
DLG5Q8TDM6not detectable10
(ALY)402PARD3BQ8TEW8not detectable10
(ALY)402PDZRN4Q6ZMN7not detectable9
TJP3O95049not detectable8
(ALY)402APBA2Q99767not detectable8
(ALY)402PDZRN3Q9UPQ7not detectable8
(ALY)402DLG5Q8TDM6not detectable7
APBA2Q99767not detectable7
APBA3O96018not detectable6
(ALY)402FRMPD4Q14CM0not detectable6
(ALY)402TJP3O95049not detectable6
FRMPD4Q14CM0not detectable5
LIN7CQ9NUP9not detectable5
(ALY)402APBA3O96018not detectable5
USH1CQ9Y6N9not detectable4
CARD11Q9BXL7not detectable4
DVL3Q92997not detectable4
FRMPD1Q5SYB0not detectable4
FRMPD3Q5JV73not detectable4
HTRA2O43464not detectable4
HTRA3P83110not detectable4
LDB3O75112not detectable4
LIN7AO14910not detectable4
LRRC7Q96NW7not detectable4
MPP2Q14168not detectable4
MPP6Q9NZW5not detectable4
MPP7Q5T2T1not detectable4
NOS1P29475not detectable4
SIPA1L2Q9P2F8not detectable4
TIAM2Q8IVF5not detectable4
(ALY)402ARHGAP21Q5T5U3not detectable4
(ALY)402CARD11Q9BXL7not detectable4
(ALY)402CASKO14936not detectable4
(ALY)402DVL3Q92997not detectable4
(ALY)402FRMPD1Q5SYB0not detectable4
(ALY)402FRMPD3Q5JV73not detectable4
(ALY)402GIPC2Q8TF65not detectable4
(ALY)402HTRA2O43464not detectable4
(ALY)402HTRA3P83110not detectable4
(ALY)402LDB3O75112not detectable4
(ALY)402LIMK2P53671not detectable4
(ALY)402LIN7AO14910not detectable4
(ALY)402LRRC7Q96NW7not detectable4
(ALY)402MPP7Q5T2T1not detectable4
(ALY)402PCLOQ9Y6V0not detectable4
(ALY)402PDLIM1O00151not detectable4
(ALY)402RAPGEF6Q8TEU7not detectable4
(ALY)402SIPA1L2Q9P2F8not detectable4
PREX1Q8TCU6not detectable3
PREX2Q70Z35not detectable3
SDCBPO00560not detectable3
PCLOQ9Y6V0not detectable3
PDLIM1O00151not detectable3
RAPGEF6Q8TEU7not detectable3
(ALY)402MPP2Q14168not detectable3
AHNAKQ9BSE5not detectable2
ARHGAP23Q9P227not detectable2
CARD14Q9BXL6not detectable2
CNKSR3Q6P9H4not detectable2
DVL1O14640not detectable2
DVL2O14641not detectable2
GIPC1O14908not detectable2
INTUQ9ULD6not detectable2
LIMK1P53667not detectable2
MAGIXQ9H6Y5not detectable2
MAST4O15021not detectable2
MLLT4P55196not detectable2
MPP1Q00013not detectable2
MPP3Q13368not detectable2
MPP4Q96JB8not detectable2
MPP5Q8N3R9not detectable2
PARD6GQ9BYG4not detectable2
PDLIM2Q96JY6not detectable2
PDLIM4P50479not detectable2
PDLIM5Q96HC4not detectable2
PDLIM7Q9NR12not detectable2
PDZD11Q5EBL8not detectable2
PDZD4Q76G19not detectable2
PDZD8Q8NEN9not detectable2
PRXQ9BXM0not detectable2
PSCDBPO60759not detectable2
PSMD9O00233not detectable2
PTPN4P29074not detectable2
RAPGEF2Q9Y4G8not detectable2
RHPN2Q8IUC4not detectable2
SDCBP2Q9H190not detectable2
SHROOM2Q13796not detectable2
SHROOM4Q9ULL8not detectable2
STXB4Q6ZWJ1not detectable2
SYNP2Q9UMS6not detectable2
SYNPO2LQ9H987not detectable2
TIAM1Q13009not detectable2
(ALY)402AHNAKQ9BSE5not detectable2
(ALY)402SDCBPO00560not detectable2
(ALY)402USH1CQ9Y6N9not detectable2
CNKSR1Q969H4not detectable1
CNKSR2Q8WXI2not detectable1
DEPTORQ8TB45not detectable1
GIPC3Q8TF64not detectable1
PARD6AQ9NPB6not detectable1
PDZD9Q8IXQ8not detectable1
PPP1R9AQ9ULJ8not detectable1
RGS12O14924not detectable1
RIMS1Q86UR5not detectable1
RIMS2Q9UQ26not detectable1
SHROOM3Q8TF72not detectable1
SIPA1Q96FS4not detectable1
SIPA1L1O43166not detectable1
SIPA1L3O60292not detectable1
AHNAK1Q09666not detectable1
AHNAK2Q8IVF2not detectable1
LMO7Q8WWI1not detectable1
SHANK2Q9UPX8not detectable1
(ALY)402AHNAK1Q09666not detectable1
(ALY)402AHNAK2Q8IVF2not detectable1
(ALY)402ARHGAP23Q9P227not detectable1
(ALY)402DEPTORQ8TB45not detectable1
(ALY)402DVL1O14640not detectable1
(ALY)402GIPC1O14908not detectable1
(ALY)402INTUQ9ULD6not detectable1
(ALY)402LIMK1P53667not detectable1
(ALY)402MAGIXQ9H6Y5not detectable1
(ALY)402MAST4O15021not detectable1
(ALY)402MPP1Q00013not detectable1
(ALY)402MPP3Q13368not detectable1
(ALY)402MPP4Q96JB8not detectable1
(ALY)402MPP5Q8N3R9not detectable1
(ALY)402MYO18AQ92614not detectable1
(ALY)402PARD6AQ9NPB6not detectable1
(ALY)402PARD6BQ9BYG5not detectable1
(ALY)402PARD6GQ9BYG4not detectable1
(ALY)402PDLIM2Q96JY6not detectable1
(ALY)402PDLIM3Q53GG5not detectable1
(ALY)402PDLIM4P50479not detectable1
(ALY)402PDLIM5Q96HC4not detectable1
(ALY)402PDLIM7Q9NR12not detectable1
(ALY)402PDZD11Q5EBL8not detectable1
(ALY)402PDZD4Q76G19not detectable1
(ALY)402PDZD8Q8NEN9not detectable1
(ALY)402PDZD9Q8IXQ8not detectable1
(ALY)402PPP1R9AQ9ULJ8not detectable1
(ALY)402PPP1R9BQ96SB3not detectable1
(ALY)402PREX1Q8TCU6not detectable1
(ALY)402PREX2Q70Z35not detectable1
(ALY)402PRXQ9BXM0not detectable1
(ALY)402PSCDBPO60759not detectable1
(ALY)402PSMD9O00233not detectable1
(ALY)402PTPN4P29074not detectable1
(ALY)402RAPGEF2Q9Y4G8not detectable1
(ALY)402RGS12O14924not detectable1
(ALY)402RGS3P49796not detectable1
(ALY)402RHPN2Q8IUC4not detectable1
(ALY)402RIMS1Q86UR5not detectable1
(ALY)402RIMS2Q9UQ26not detectable1
(ALY)402SDCBP2Q9H190not detectable1
(ALY)402SHROOM2Q13796not detectable1
(ALY)402SHROOM3Q8TF72not detectable1
(ALY)402SHROOM4Q9ULL8not detectable1
(ALY)402SIPA1L3O60292not detectable1
(ALY)402STXB4Q6ZWJ1not detectable1
(ALY)402SYNP2Q9UMS6not detectable1
(ALY)402SYNPO2LQ9H987not detectable1
(ALY)402TIAM1Q13009not detectable1





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