ProfAff

You are looking at the quantitative interactomic profile of the non-modified proteoform of DNM2

UniProt ID: P50570
Molecule ID: DNM2 (Link to all interactions of this molecule.)
Alternative name(s): DNM2 DYN2

The selection have 1 unique variants
non-modified profile

You accessed the interactomic profile with a defined modification. See all possible variants of the same selection.

The selection have 9 unique fragments
full-length protein (1-870)
313-327 fragment
801-815 fragment
823-837 fragment
823-860 fragment
826-840 fragment
834-848 fragment
838-852 fragment
846-860 fragment

The selection have 7 unique sites
PxxP_1 sites
PxxP_2 sites
PxxP_3 sites
PxxP_4 sites
PxxP_5 sites
PxxP_6 sites
PxxP_7 sites

You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.

Partners			Experiment
ID	UniProt	Modification	pK_d Any affinities measured between the same molecules, unless modification-dependent, are averaged on this page.	St.dev Standard deviation is calculated using affinities obtained from independent experiment series. * indicates that affinity was not detectable in all experiments	n	QI Quality indicator n > 1 and St.dev < 0.5 pKd n > 1 and St.dev > 0.5 pKd or only detectable in a subset of experiment series n > 1, but originating from a single experiment series n = 1
BIN1	O00499	V583I	4.54	0.29*	27, detectable in 11
BIN1	O00499	P551L	4.52	0.16*	24, detectable in 8
AMPH	P49418		4.50	0.54*	21, detectable in 17
PRMT2	P55345		4.45	0.76*	21, detectable in 5
ARHGEF7	Q14155		4.44	0.45*	21, detectable in 17
BIN1	O00499	R581C	4.37	0.32*	24, detectable in 10
BIN1	O00499	V566M	4.33	0.33*	36, detectable in 24
BIN1	O00499		4.30	0.72*	58, detectable in 48
BIN1	O00499	Q540H	4.28	0.45*	36, detectable in 30
BIN1	O00499	T532M	4.17	0.38*	52, detectable in 32
ABL1	P00519		3.99	0.47*	21, detectable in 14
BIN1	O00499	Y531S	3.52	*	36, detectable in 2
BIN1	O00499	D537V	not detectable		36
BIN1	O00499	F584S	not detectable		36
SNX27	Q96L92		not detectable		21
OBSCN	Q5VST9		not detectable		21
DLG1	Q12959		not detectable		6
SCRIB	Q14160		not detectable		6
TX1BP3	O14907		not detectable		3

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