You are looking at the quantitative interactomic profile of the molecule of MAP2K2


UniProt ID: P36507
Molecule ID: MAP2K2 (Link to all interactions of this molecule.)
Alternative name(s): MEK2 MKK2 PRKMK2


The selection have 1 unique variants
non-modified profile

The selection have 2 unique fragments
full-length protein (1-400)
391-400 fragment

The selection have 1 unique sites
PBM sites







You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


Partners Experiment
IDUniProtpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
DVL2O146414.801
GRID2IPA4D2P64.620.36*4, detectable in 2
GRASPQ7Z6J24.600.042
SIPA1L2Q9P2F84.43*2, detectable in 1
CASKO149364.38*2, detectable in 1
PDZD7Q9H5P44.36*4, detectable in 1
MAST2Q6P0Q84.34*2, detectable in 1
DLG1Q129594.300.47*12, detectable in 5
PDZD4Q76G194.211
LIMK1P536674.201
DFNB31Q9P2024.16*5, detectable in 1
DLG4P783524.12*7, detectable in 1
SHANK1Q9Y5664.120.052
MPP1Q000134.121
PARD3BQ8TEW84.07*4, detectable in 1
CNKSR1Q969H44.071
CNKSR3Q6P9H44.051
PDZD2O150184.040.24*7, detectable in 2
TX1BP3O149073.97*5, detectable in 1
APBA1Q024103.960.34*4, detectable in 2
NOS1P294753.96*2, detectable in 1
DLG3Q927963.93*4, detectable in 1
DLG2Q157003.890.02*5, detectable in 2
MAGI3Q5TCQ93.84*7, detectable in 1
InadlQ8NI353.78*20, detectable in 1
MAGI2Q86UL83.720.17*11, detectable in 5
TJP2Q9UDY23.71*4, detectable in 1
RAPGEF6Q8TEU73.67*2, detectable in 1
PTPN13Q129233.66*6, detectable in 1
ARHGEF12Q9NZN53.66*2, detectable in 1
SNTG1Q9NSN83.66*2, detectable in 1
LNX1Q8TBB13.630.03*6, detectable in 3
TJP3O950493.57*4, detectable in 1
PARD3Q8TEW03.54*4, detectable in 1
RADILQ96JH83.54*2, detectable in 1
MPDZO759703.540.05*16, detectable in 2
NHERF4Q86UT53.52*7, detectable in 1
MPP6Q9NZW53.52*2, detectable in 1
HTRA3P831103.50*2, detectable in 1
PDLIM1O001513.47*2, detectable in 1
SNX27Q96L92not detectable25
SCRIBQ14160not detectable16
GRIP1Q9Y3R0not detectable12
GRIP2Q9C0E4not detectable12
MAGI1Q96QZ7not detectable8
IL16Q14005not detectable7
NHERF3Q5T2W1not detectable7
BIN1O00499not detectable6
FRMPD2Q68DX3not detectable6
TJP1Q07157not detectable5
APBA2Q99767not detectable4
LNX2Q8N448not detectable4
ABL1P00519not detectable3
AMPHP49418not detectable3
ARHGEF7Q14155not detectable3
OBSCNQ5VST9not detectable3
PRMT2P55345not detectable3
APBA3O96018not detectable3
LAP2Q96RT1not detectable3
NHERF2Q15599not detectable3
PDZRN3Q9UPQ7not detectable3
PDZRN4Q6ZMN7not detectable3
USH1CQ9Y6N9not detectable3
AHNAK1Q09666not detectable2
ARHGAP21Q5T5U3not detectable2
ARHGEF11O15085not detectable2
DLG5Q8TDM6not detectable2
DVL3Q92997not detectable2
FRMPD1Q5SYB0not detectable2
FRMPD3Q5JV73not detectable2
FRMPD4Q14CM0not detectable2
GIPC2Q8TF65not detectable2
GOPCQ9HD26not detectable2
GORASP1Q9BQQ3not detectable2
GORASP2Q9H8Y8not detectable2
HTRA1Q92743not detectable2
HTRA2O43464not detectable2
HTRA4P83105not detectable2
LDB3O75112not detectable2
LIMK2P53671not detectable2
LIN7AO14910not detectable2
LIN7BQ9HAP6not detectable2
LIN7CQ9NUP9not detectable2
LRRC7Q96NW7not detectable2
MAST1Q9Y2H9not detectable2
MPP2Q14168not detectable2
MPP7Q5T2T1not detectable2
NHERF1O14745not detectable2
PCLOQ9Y6V0not detectable2
PICK1Q9NRD5not detectable2
PREX2Q70Z35not detectable2
PTPN3P26045not detectable2
RHPN1Q8TCX5not detectable2
SDCBPO00560not detectable2
SDCBP2Q9H190not detectable2
SNTA1Q13424not detectable2
SNTB1Q13884not detectable2
SNTG2Q9NY99not detectable2
SYNJ2BPP57105not detectable2
TIAM2Q8IVF5not detectable2
AHNAK2Q8IVF2not detectable1
ARHGAP23Q9P227not detectable1
CARD11Q9BXL7not detectable1
CARD14Q9BXL6not detectable1
DVL1O14640not detectable1
GIPC1O14908not detectable1
GIPC3Q8TF64not detectable1
INTUQ9ULD6not detectable1
LMO7Q8WWI1not detectable1
MAGIXQ9H6Y5not detectable1
MAST3O60307not detectable1
MAST4O15021not detectable1
MLLT4P55196not detectable1
MPP3Q13368not detectable1
MPP4Q96JB8not detectable1
MPP5Q8N3R9not detectable1
MYO18AQ92614not detectable1
PARD6AQ9NPB6not detectable1
PARD6BQ9BYG5not detectable1
PARD6GQ9BYG4not detectable1
PDLIM2Q96JY6not detectable1
PDLIM3Q53GG5not detectable1
PDLIM4P50479not detectable1
PDLIM5Q96HC4not detectable1
PDLIM7Q9NR12not detectable1
PDZD11Q5EBL8not detectable1
PDZD8Q8NEN9not detectable1
PDZD9Q8IXQ8not detectable1
PPP1R9AQ9ULJ8not detectable1
PPP1R9BQ96SB3not detectable1
PREX1Q8TCU6not detectable1
PSCDBPO60759not detectable1
PSMD9O00233not detectable1
PTPN4P29074not detectable1
RGS12O14924not detectable1
RGS3P49796not detectable1
RHPN2Q8IUC4not detectable1
RIMS1Q86UR5not detectable1
RIMS2Q9UQ26not detectable1
SHANK2Q9UPX8not detectable1
SHANK3Q9BYB0not detectable1
SHROOM2Q13796not detectable1
SHROOM3Q8TF72not detectable1
SHROOM4Q9ULL8not detectable1
SIPA1Q96FS4not detectable1
SIPA1L1O43166not detectable1
SIPA1L3O60292not detectable1
SNTB2Q13425not detectable1
STXB4Q6ZWJ1not detectable1
SYNP2Q9UMS6not detectable1
SYNPO2LQ9H987not detectable1
TIAM1Q13009not detectable1





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