You are looking at the quantitative interactomic profile of the molecule of HPV16-E6


UniProt ID: P03126
Molecule ID: HPV16-E6 (Link to all interactions of this molecule.)
Alternative name(s): E6


The selection have 2 unique variants
non-modified profile
(TPO)156 modified profile

The selection have 2 unique fragments
139-149 fragment
149-158 fragment

The selection have 2 unique sites
14-3-3_pThr156 sites
PBM sites







You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


SelectionPartners Experiment
ModificationIDUniProtpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
PDZRN3Q9UPQ75.570.21*16, detectable in 12
MAST2Q6P0Q85.460.1016
SCRIBQ141605.200.52*56, detectable in 47
PDZRN4Q6ZMN75.190.08*19, detectable in 13
SYNJ2BPP571055.180.2117
MAGI1Q96QZ75.050.72*45, detectable in 25
NHERF3Q5T2W15.040.78*42, detectable in 19
MAGI3Q5TCQ95.030.88*41, detectable in 18
DLG4P783524.980.2239
SNX27Q96L924.890.08*21, detectable in 20
MAST1Q9Y2H94.890.30*15, detectable in 14
SNTB1Q138844.880.1214
ARHGEF12Q9NZN54.870.1416
PTPN3P260454.870.0912
TX1BP3O149074.860.0511
MAGI2Q86UL84.840.81*60, detectable in 24
DLG2Q157004.800.2429
DLG1Q129594.790.1433
RHPN1Q8TCX54.790.329
DLG3Q927964.670.3834
PDZD7Q9H5P44.630.08*28, detectable in 14
PTPN4P290744.618
(TPO)156GRIP1Q9Y3R04.61*12, detectable in 1
(TPO)156PCLOQ9Y6V04.54*2, detectable in 1
SNTA1Q134244.530.1914
(TPO)156USH1CQ9Y6N94.45*3, detectable in 1
RGS12O149244.376
NHERF2Q155994.290.12*17, detectable in 10
TJP2Q9UDY24.280.14*26, detectable in 11
ARHGEF11O150854.260.1111
(TPO)156PDZRN4Q6ZMN74.26*6, detectable in 1
TJP1Q071574.22*30, detectable in 8
NHERF4Q86UT54.210.18*37, detectable in 19
LIN7CQ9NUP94.210.1110
SNTG2Q9NY994.160.18*15, detectable in 14
LMO7Q8WWI14.156
(TPO)156NHERF4Q86UT54.140.22*7, detectable in 2
(TPO)156FRMPD4Q14CM04.140.262
GIPC1O149084.136
SNTB2Q134254.126
DLG5Q8TDM64.12*36, detectable in 8
(TPO)156ARHGAP21Q5T5U34.110.062
FRMPD4Q14CM04.100.1412
(TPO)156SIPA1L2Q9P2F84.09*2, detectable in 1
MPDZO759704.060.24*97, detectable in 9
PDZD9Q8IXQ84.065
APBA1Q024104.040.24*16, detectable in 5
GRID2IPA4D2P64.030.19*21, detectable in 7
NOS1P294754.030.059
GORASP2Q9H8Y84.02*13, detectable in 2
NHERF1O147454.010.1313
FRMPD2Q68DX34.000.19*35, detectable in 12
LNX2Q8N4484.00*31, detectable in 7
GOPCQ9HD264.000.14*16, detectable in 15
(TPO)156TX1BP3O149073.981
(TPO)156LIN7CQ9NUP93.941
USH1CQ9Y6N93.92*26, detectable in 8
(TPO)156PTPN3P260453.92*2, detectable in 1
ARHGAP21Q5T5U33.92*10, detectable in 1
PDLIM1O001513.910.12*10, detectable in 9
LRRC7Q96NW73.910.159
LIN7BQ9HAP63.900.0310
(TPO)156DFNB31Q9P2023.89*6, detectable in 1
PDLIM3Q53GG53.887
(TPO)156NHERF3Q5T2W13.80*10, detectable in 4
(TPO)156MAST2Q6P0Q83.79*5, detectable in 1
SNTG1Q9NSN83.730.08*10, detectable in 3
TJP3O950493.68*26, detectable in 1
LIN7AO149103.670.17*11, detectable in 2
RAPGEF6Q8TEU73.66*11, detectable in 1
PARD3Q8TEW03.65*24, detectable in 1
RADILQ96JH83.65*10, detectable in 1
DFNB31Q9P2023.640.15*36, detectable in 3
(TPO)156NOS1P294753.63*2, detectable in 1
IL16Q140053.62*41, detectable in 1
SHANK1Q9Y5663.620.05*10, detectable in 2
InaDlQ8NI353.600.18*110, detectable in 6
MPP6Q9NZW53.58*10, detectable in 1
PTPN13Q129233.56*41, detectable in 1
LAP2Q96RT13.53*15, detectable in 1
GORASP1Q9BQQ33.52*12, detectable in 2
LNX1Q8TBB13.500.02*29, detectable in 3
GRIP2Q9C0E43.48*69, detectable in 1
(TPO)156MAGI1Q96QZ72.60*10, detectable in 3
GRIP1Q9Y3R0not detectable74
PDZD2O15018not detectable43
PARD3BQ8TEW8not detectable28
APBA2Q99767not detectable18
APBA3O96018not detectable16
HTRA1Q92743not detectable16
SDCBPO00560not detectable16
(TPO)156InadlQ8NI35not detectable16
(TPO)156MPDZO75970not detectable16
SDCBP2Q9H190not detectable14
(TPO)156MAGI2Q86UL8not detectable14
FRMPD1Q5SYB0not detectable12
FRMPD3Q5JV73not detectable12
GIPC2Q8TF65not detectable12
GRASPQ7Z6J2not detectable12
LDB3O75112not detectable12
LIMK2P53671not detectable12
(TPO)156SCRIBQ14160not detectable12
CASKO14936not detectable11
HTRA3P83110not detectable11
HTRA4P83105not detectable11
PREX1Q8TCU6not detectable11
PREX2Q70Z35not detectable11
TIAM2Q8IVF5not detectable11
DVL3Q92997not detectable10
MPP2Q14168not detectable10
MPP7Q5T2T1not detectable10
PCLOQ9Y6V0not detectable10
PICK1Q9NRD5not detectable10
SIPA1L2Q9P2F8not detectable10
CARD11Q9BXL7not detectable9
HTRA2O43464not detectable9
PPP1R9AQ9ULJ8not detectable8
PSCDBPO60759not detectable8
PSMD9O00233not detectable8
RGS3P49796not detectable8
RHPN2Q8IUC4not detectable8
RIMS1Q86UR5not detectable8
SHANK3Q9BYB0not detectable8
SHROOM2Q13796not detectable8
SHROOM3Q8TF72not detectable8
SHROOM4Q9ULL8not detectable8
SIPA1Q96FS4not detectable8
STXB4Q6ZWJ1not detectable8
SYNP2Q9UMS6not detectable8
TIAM1Q13009not detectable8
(TPO)156DLG4P78352not detectable8
AHNAK2Q8IVF2not detectable7
ARHGAP23Q9P227not detectable7
CARD14Q9BXL6not detectable7
INTUQ9ULD6not detectable7
LIMK1P53667not detectable7
MAST3O60307not detectable7
MAST4O15021not detectable7
MLLT4P55196not detectable7
MPP1Q00013not detectable7
MPP3Q13368not detectable7
MPP4Q96JB8not detectable7
MPP5Q8N3R9not detectable7
MYO18AQ92614not detectable7
PARD6AQ9NPB6not detectable7
PDLIM2Q96JY6not detectable7
PDLIM4P50479not detectable7
PDLIM5Q96HC4not detectable7
PDZD11Q5EBL8not detectable7
PDZD8Q8NEN9not detectable7
PPP1R9BQ96SB3not detectable7
PRXQ9BXM0not detectable7
RIMS2Q9UQ26not detectable7
SHANK2Q9UPX8not detectable7
SIPA1L3O60292not detectable7
SYNPO2LQ9H987not detectable7
(TPO)156GRIP2Q9C0E4not detectable7
(TPO)156PARD3BQ8TEW8not detectable7
(TPO)156PDZD2O15018not detectable7
AHNAK1Q09666not detectable6
DEPTORQ8TB45not detectable6
DVL2O14641not detectable6
MAGIXQ9H6Y5not detectable6
PARD6GQ9BYG4not detectable6
PDLIM7Q9NR12not detectable6
PDZD4Q76G19not detectable6
RAPGEF2Q9Y4G8not detectable6
SIPA1L1O43166not detectable6
(TPO)156DLG3Q92796not detectable6
(TPO)156FRMPD2Q68DX3not detectable6
(TPO)156GRID2IPA4D2P6not detectable6
(TPO)156IL16Q14005not detectable6
(TPO)156LNX2Q8N448not detectable6
(TPO)156MAGI3Q5TCQ9not detectable6
(TPO)156PDZD7Q9H5P4not detectable6
(TPO)156PTPN13Q12923not detectable6
CNKSR2Q8WXI2not detectable5
CNKSR3Q6P9H4not detectable5
DVL1O14640not detectable5
(TPO)156ARHGEF12Q9NZN5not detectable5
(TPO)156DLG1Q12959not detectable5
(TPO)156DLG5Q8TDM6not detectable5
(TPO)156GOPCQ9HD26not detectable5
(TPO)156HTRA1Q92743not detectable5
(TPO)156MAST1Q9Y2H9not detectable5
(TPO)156SNTA1Q13424not detectable5
(TPO)156SNTB1Q13884not detectable5
(TPO)156SNTG2Q9NY99not detectable5
(TPO)156SYNJ2BPP57105not detectable5
(TPO)156TJP1Q07157not detectable5
CNKSR1Q969H4not detectable4
PARD6BQ9BYG5not detectable4
(TPO)156DLG2Q15700not detectable4
(TPO)156LNX1Q8TBB1not detectable4
(TPO)156PARD3Q8TEW0not detectable4
(TPO)156PDZRN3Q9UPQ7not detectable4
(TPO)156TJP2Q9UDY2not detectable4
(TPO)156TJP3O95049not detectable4
(TPO)156YWHAGP61981not detectable4
GIPC3Q8TF64not detectable3
(TPO)156APBA2Q99767not detectable3
(TPO)156NHERF2Q15599not detectable3
AHNAKQ9BSE5not detectable2
(TPO)156APBA1Q02410not detectable2
(TPO)156APBA3O96018not detectable2
(TPO)156ARHGEF11O15085not detectable2
(TPO)156CASKO14936not detectable2
(TPO)156DVL3Q92997not detectable2
(TPO)156FRMPD1Q5SYB0not detectable2
(TPO)156FRMPD3Q5JV73not detectable2
(TPO)156GIPC2Q8TF65not detectable2
(TPO)156GORASP1Q9BQQ3not detectable2
(TPO)156GORASP2Q9H8Y8not detectable2
(TPO)156GRASPQ7Z6J2not detectable2
(TPO)156HTRA3P83110not detectable2
(TPO)156HTRA4P83105not detectable2
(TPO)156LAP2Q96RT1not detectable2
(TPO)156LDB3O75112not detectable2
(TPO)156LIMK2P53671not detectable2
(TPO)156LIN7AO14910not detectable2
(TPO)156LIN7BQ9HAP6not detectable2
(TPO)156LRRC7Q96NW7not detectable2
(TPO)156MPP2Q14168not detectable2
(TPO)156MPP6Q9NZW5not detectable2
(TPO)156MPP7Q5T2T1not detectable2
(TPO)156NHERF1O14745not detectable2
(TPO)156PDLIM1O00151not detectable2
(TPO)156PICK1Q9NRD5not detectable2
(TPO)156RADILQ96JH8not detectable2
(TPO)156RAPGEF6Q8TEU7not detectable2
(TPO)156RHPN1Q8TCX5not detectable2
(TPO)156SDCBPO00560not detectable2
(TPO)156SHANK1Q9Y566not detectable2
(TPO)156SNTG1Q9NSN8not detectable2
(TPO)156SNX27Q96L92not detectable2
(TPO)156TIAM2Q8IVF5not detectable2
(TPO)156AHNAK1Q09666not detectable1
(TPO)156AHNAK2Q8IVF2not detectable1
(TPO)156CARD11Q9BXL7not detectable1
(TPO)156CNKSR3Q6P9H4not detectable1
(TPO)156HTRA2O43464not detectable1
(TPO)156LIMK1P53667not detectable1
(TPO)156MAGIXQ9H6Y5not detectable1
(TPO)156MAST3O60307not detectable1
(TPO)156MAST4O15021not detectable1
(TPO)156MLLT4P55196not detectable1
(TPO)156MPP1Q00013not detectable1
(TPO)156MPP3Q13368not detectable1
(TPO)156MPP4Q96JB8not detectable1
(TPO)156MPP5Q8N3R9not detectable1
(TPO)156MYO18AQ92614not detectable1
(TPO)156PARD6AQ9NPB6not detectable1
(TPO)156PDLIM2Q96JY6not detectable1
(TPO)156PDLIM3Q53GG5not detectable1
(TPO)156PDLIM4P50479not detectable1
(TPO)156PDLIM5Q96HC4not detectable1
(TPO)156PDLIM7Q9NR12not detectable1
(TPO)156PDZD11Q5EBL8not detectable1
(TPO)156PDZD4Q76G19not detectable1
(TPO)156PDZD8Q8NEN9not detectable1
(TPO)156PPP1R9AQ9ULJ8not detectable1
(TPO)156PPP1R9BQ96SB3not detectable1
(TPO)156PREX1Q8TCU6not detectable1
(TPO)156PREX2Q70Z35not detectable1
(TPO)156PRXQ9BXM0not detectable1
(TPO)156PSCDBPO60759not detectable1
(TPO)156PSMD9O00233not detectable1
(TPO)156PTPN4P29074not detectable1
(TPO)156RGS3P49796not detectable1
(TPO)156RHPN2Q8IUC4not detectable1
(TPO)156RIMS1Q86UR5not detectable1
(TPO)156SDCBP2Q9H190not detectable1
(TPO)156SHANK2Q9UPX8not detectable1
(TPO)156SHANK3Q9BYB0not detectable1
(TPO)156SHROOM2Q13796not detectable1
(TPO)156SHROOM3Q8TF72not detectable1
(TPO)156SHROOM4Q9ULL8not detectable1
(TPO)156SIPA1Q96FS4not detectable1
(TPO)156SIPA1L3O60292not detectable1
(TPO)156STXB4Q6ZWJ1not detectable1
(TPO)156SYNP2Q9UMS6not detectable1
(TPO)156SYNPO2LQ9H987not detectable1
(TPO)156TIAM1Q13009not detectable1





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