You are looking at the quantitative interactomic profile of the molecule of HTRA2


UniProt ID: O43464
Molecule ID: HTRA2 (Link to all interactions of this molecule.)
Alternative name(s): OMI PRSS25


The selection have 1 unique variants
non-modified profile

The selection have 2 unique fragments
full-length protein (1-458)
355-458 fragment

The selection have 1 unique sites
PDZ sites







You see an affinity binding profile calculated for macromolecular interactions, where affinities measured using different fragments of the same proteins are combined. To only show affinities of a specific fragment or functional site, select one on the top of the page.

Be careful with the reported affinities and standard deviations because they may be based on an array of measurements performed with unrelated fragments. Always inspect the origin of the measured affinity values by clicking on the reported pKd value in the table.


Partners Experiment
IDUniProtModificationpKd
Any affinities measured between
the same molecules,
unless modification-dependent,
are averaged on this page.
St.dev
Standard deviation is calculated
using affinities obtained from
independent experiment series.


* indicates that affinity was
not detectable in all
experiments
nQI
Quality indicator
n > 1 and St.dev < 0.5 pKd
n > 1 and St.dev > 0.5 pKd
or only detectable in a subset
of experiment series
n > 1, but originating
from a single experiment series
n = 1
PKN2Q165135.111
FZD7O750844.90*2, detectable in 1
YAP1P469374.731
CSPG4Q6UVK14.721
TRAF7Q6Q0C04.681
DCAF7P619624.661
NECTIN3Q9NQS34.601
MCM7P339934.521
WWTR1Q9GZV54.511
GNG4P501504.491
CLDN2P577394.481
CLDN8P567484.461
FAM167BQ9BTA04.441
LNX2Q8N4484.421
MMP24Q9Y5R24.401
EFNB3Q157684.301
GJC1P363834.251
NECTIN1Q152234.201
EFNB1P527994.181
TTC24A2A3L64.181
CTNND2Q9UQB34.121
GYPCP049214.101
LPXNO607114.101
SDK2Q58EX24.071
SLC6A3Q019594.061
PKP4Q995694.051
MERS-EK9N5R34.020.264
NRXN3Q9HDB54.021
GAS2L2Q8NHY33.961
PRKNO602603.961
RGS12O149243.950.022
GJD4Q96KN93.941
LNX1Q8TBB13.941
FCHSD2O948683.931
BANF1O755313.911
JAG1P785043.881
JAM2P570873.881
ASIC3Q9UHC33.860.05*3, detectable in 2
FAM71CQ8NEG03.851
CACNA1DQ016683.831
MARCHF4Q9P2E83.831
AGMATQ9BSE53.802
JAM1Q9Y6243.781
PTGIRP431193.781
FZD10Q9ULW23.761
RPS6KA1Q15418(SEP)7323.75*5, detectable in 2
APCP250543.74*2, detectable in 1
CLDN14O955003.741
NPSR1Q6W5P43.721
CLDN18P568563.711
GRASPQ7Z6J23.69*2, detectable in 1
PDLIM4P50479iso23.691
ABCC4O154393.68*4, detectable in 2
ARVCFO001923.681
TMEM215Q68D423.681
TRIM29Q141343.681
PPFIA1Q131363.661
TMEM178AQ8NBL33.651
NF2P352403.611
EPHB3P547533.591
MARCHF9Q86YJ53.561
FZD1Q9UP383.551
RPS6KA3P518123.551
AKIP1Q9NQ313.541
CCRL2O004213.541
APBA1Q024103.531
SRCP129313.531
PODXLO005923.521
SLC15A2Q163483.521
NRXN3Q9Y4C0rs7464442063.511
RNF130Q86XS83.511
CYSLTR2Q9NS753.50*3, detectable in 1
CIB2O758383.501
CNTNAP2Q9UHC63.491
HPV49-L2P367623.491
RPS6KA1Q15418(TPO)7343.491
PDZRN3Q9UPQ73.481
VAC14Q08AM63.481
HPV33-E6P064273.46*2, detectable in 1
HPV16-E6P03126not detectable9
DLG1Q12959not detectable6
SCRIBQ14160not detectable6
RPS6KA1Q15418not detectable6
ARHGEF7Q14155not detectable5
WNV-NS5Q9Q6P4not detectable5
HPV18-E6P06463not detectable4
HPV35-E6P27228not detectable4
HTLV1-TAX1P03409not detectable4
NET1Q7Z628not detectable4
PTENP60484not detectable4
PTENP60484(ALY)402not detectable4
SLC15A5A6NIM6not detectable4
SLCO1C1Q9NYB5not detectable4
ABL1P00519not detectable3
AMPHP49418not detectable3
BIN1O00499not detectable3
OBSCNQ5VST9not detectable3
PRMT2P55345not detectable3
SNX27Q96L92not detectable3
TX1BP3O14907not detectable3
ARHGEF26Q96DR7not detectable3
ATP2B1P20020not detectable3
ATP2B4P23634not detectable3
DGKZQ13574not detectable3
FRMPD4Q14CM0not detectable3
HBV-HbcP03146not detectable3
KCNA4P22459not detectable3
OTULINQ96BN8not detectable3
PLCB4Q15147not detectable3
RALBP1Q15311not detectable3
ABCA1O95477not detectable2
ACE2Q9BYF1not detectable2
ARHGEF16Q5VV41not detectable2
CACNG4Q9UBN1not detectable2
CBPQ92793not detectable2
CFTRP13569not detectable2
CTNNB1P35222not detectable2
DFNB31Q9P202not detectable2
DGKKQ5KSL6not detectable2
DOCK4Q8N1I0not detectable2
FAT3Q8TDW7not detectable2
FRMPD1Q5SYB0not detectable2
HPV30-E6P36809not detectable2
HPV51-E6P26554not detectable2
HPV59-E6Q81964not detectable2
HPV67-E6A4U7F2not detectable2
HPV73-E6Q82005not detectable2
HPV82-E6Q9IR59not detectable2
KCNA5P22460not detectable2
KIR3DL3Q8N743not detectable2
MAP2K2P36507not detectable2
MAPK12P53778not detectable2
PBKQ96KB5not detectable2
RASSF6Q6ZTQ3not detectable2
SARS-CoV2-EP0DTC4not detectable2
SARS-Cov-EP59637not detectable2
SARS-Cov2-3aP0DTC3not detectable2
SARS-Cov2-NP0DTC9not detectable2
SLC2A1P11166not detectable2
TANC2Q9HCD6not detectable2
TJP2Q9UDY2not detectable2
ABCA2Q9BZC7not detectable1
ABCA7Q8IZY2not detectable1
ABCC6O95255not detectable1
ABRAXAS2Q15018not detectable1
ACOT6Q3I5F7not detectable1
ACOT8O14734not detectable1
ACTN2P35609not detectable1
ACVR2AP27037not detectable1
ADAM17P78536not detectable1
ADAM22Q9P0K1not detectable1
ADGRA1Q86SQ6not detectable1
ADGRA2Q96PE1not detectable1
ADGRA3Q8IWK6not detectable1
ADGRE5P48960not detectable1
ADGRG1Q9Y653not detectable1
ADRA1DP25100not detectable1
ADRB1P08588not detectable1
ADRB2P07550not detectable1
AKAP10O43572not detectable1
AMOTL1Q8IY63not detectable1
APPL1Q9UKG1not detectable1
AQP3Q92482not detectable1
AQP6Q13520not detectable1
ARAP3Q8WWN8not detectable1
ARHGAP17Q68EM7not detectable1
ARHGAP6O43182not detectable1
ASNSD1Q9NWL6not detectable1
ATP2A2P16615not detectable1
ATRNL1Q5VV63not detectable1
AXIN1O15169not detectable1
BAZ1AQ9NRL2not detectable1
BCRP11274not detectable1
BPIFA2Q96DR5not detectable1
C3AR1Q16581not detectable1
CACNA1AO00555not detectable1
CACNG2Q9Y698not detectable1
CACNG8Q8WXS5not detectable1
CACYBPQ9HB71not detectable1
CAPN6Q9Y6Q1not detectable1
CAVIN3Q969G5not detectable1
CBY2Q8NA61not detectable1
CCDC134Q9H6E4not detectable1
CCL24O00175not detectable1
CD226Q15762not detectable1
CD46P15529not detectable1
CDK18Q07002not detectable1
CES2O00748not detectable1
CES3Q6UWW8not detectable1
CGNQ9P2M7not detectable1
CITO14578not detectable1
CLDN1O95832not detectable1
CLDN10P78369not detectable1
CLDN19Q8N6F1not detectable1
CLDN20P56880not detectable1
CLDN3O15551not detectable1
CLDN4O14493not detectable1
CLDN7O95471not detectable1
CLDN9O95484not detectable1
CNKSR2Q8WXI2not detectable1
CNTNAP4Q9C0A0not detectable1
COMMD3Q9UBI1not detectable1
CRB2Q5IJ48not detectable1
CRHR1P34998not detectable1
CRIPTQ9P021not detectable1
CTBP1Q13363not detectable1
CTNNA1P35221not detectable1
CTNNA2P26232not detectable1
CXCR1P25024not detectable1
DACT1Q9NYF0not detectable1
DCHS2Q6V1P9not detectable1
DENND5AQ6IQ26not detectable1
DGKHQ86XP1not detectable1
DGKIO75912not detectable1
DLGAP4Q9Y2H0not detectable1
DLL1O00548not detectable1
DUSP10Q9Y6W6not detectable1
DUSP5Q16690not detectable1
EGLN1Q9GZT9not detectable1
EPHA6Q9UF33not detectable1
EPHA7Q15375not detectable1
EPHB6O15197not detectable1
ERBB2P04626not detectable1
ERBB4Q15303not detectable1
EVI5O60447not detectable1
EXOC4Q96A65not detectable1
EZH1Q92800not detectable1
FAM110BQ8TC76not detectable1
FAM110DQ8TAY7not detectable1
FAT1Q14517not detectable1
FKBP4Q02790not detectable1
FLVCR1Q9Y5Y0not detectable1
FMNL3Q8IVF7not detectable1
FOXI1Q12951not detectable1
FZD2Q14332not detectable1
FZD4Q9ULV1not detectable1
FZD8Q9H461not detectable1
GAB3Q8WWW8not detectable1
GAGE12JA6NER3not detectable1
GDAQ9Y2T3not detectable1
GHRHRQ02643not detectable1
GJA1P17302not detectable1
GJD2Q9UKL4not detectable1
GLAP06280not detectable1
GOLT1AQ6ZVE7not detectable1
GOT1L1Q8NHS2not detectable1
GPR12P47775not detectable1
GPR6P46095not detectable1
GPRC6AQ5T6X5not detectable1
GRIA2P42262not detectable1
GRIA3P42263not detectable1
GRID2O43424not detectable1
GRIK2Q13002not detectable1
GRIN1Q05586not detectable1
GRIN2AQ12879not detectable1
GRIN2BQ13224not detectable1
GRIN2CQ14957not detectable1
GRIP1Q9Y3R0not detectable1
GRK6P43250not detectable1
GRM5P41594not detectable1
GUCY1A2P33402not detectable1
HCN2Q9UL51not detectable1
HDAC7Q8WUI4not detectable1
HNRNPKP61978not detectable1
HPV16-E6P03126(TPO)156not detectable1
HPV18-E6P06463(TPO)156not detectable1
HPV31-E6P17386not detectable1
HPV33-E6P06427(TPO)147not detectable1
HPV35-E6P27228(TPO)147not detectable1
HSPA5P11021not detectable1
HTR2AP28223not detectable1
HTR2CP28335not detectable1
IGF1RP08069not detectable1
IGSF5Q9NSI5not detectable1
IQSEC2Q5JU85not detectable1
ITKQ08881not detectable1
JAM3Q9BX67not detectable1
JUPP14923not detectable1
KARS1Q15046not detectable1
KCNA1Q09470not detectable1
KCNA6P17658not detectable1
KCNA7Q96RP8not detectable1
KCNB1Q14721not detectable1
KCNJ1P48048not detectable1
KCNJ12Q14500not detectable1
KCNJ18B7U540not detectable1
KCNJ4P48050not detectable1
KCNJ9Q92806not detectable1
KCNT1Q5JUK3not detectable1
KCNT2Q6UVM3not detectable1
KCNV1Q6PIU1not detectable1
KCTD3Q9Y597not detectable1
KIDINS220Q9ULH0not detectable1
KIF17Q9P2E2not detectable1
KIRREL1Q96J84not detectable1
KIRREL2Q6UWL6not detectable1
KITP10721not detectable1
KLHDC7AQ5VTJ3not detectable1
LPAR1Q92633not detectable1
LRP4O75096not detectable1
LRRC4Q9HBW1not detectable1
LRRC4BQ9NT99not detectable1
LSM14AQ8ND56not detectable1
MAP4P27816not detectable1
MAP7D2Q96T17not detectable1
MARCHF3Q86UD3not detectable1
MAS1P04201not detectable1
MCCP23508not detectable1
MKNK1Q9BUB5not detectable1
MLLT4P55196not detectable1
MTMR1Q13613not detectable1
MTNR1AP48039not detectable1
MUC3AQ02505not detectable1
MUC3BQ9H195not detectable1
MYO18AQ92614not detectable1
MYOTQ9UBF9not detectable1
MYOZ1Q9NP98not detectable1
MYOZ2Q9NPC6not detectable1
MYOZ3Q8TDC0not detectable1
MYPNQ86TC9not detectable1
NCBP2LA6PVI3not detectable1
NCF1P14598not detectable1
NDE1Q9NXR1not detectable1
NEBP20929not detectable1
NHERF1O14745not detectable1
NHERF2Q15599not detectable1
NHERF3Q5T2W1not detectable1
NLGN2Q8NFZ4not detectable1
NLGN4XQ8N0W4not detectable1
NOS1APO75052not detectable1
NOSTRINQ8IVI9not detectable1
NRXN1Q9ULB1not detectable1
OR10G3Q8NGC4not detectable1
OR8G1Q15617not detectable1
PALLSQ8WX93not detectable1
PDGFRBP09619not detectable1
PDLIM2Q96JY6not detectable1
PDLIM4P50479not detectable1
PDLIM7Q9NR12not detectable1
PDZRN4Q6ZMN7not detectable1
PFKMP08237not detectable1
PLCB1Q9NQ66not detectable1
PLCB2Q00722not detectable1
PLEKHA1Q9HB21not detectable1
PLEKHA2Q9HB19not detectable1
PLEKHG7Q6ZR37not detectable1
PLEKHH2Q8IVE3not detectable1
PLXNB1O43157not detectable1
POLR1DP0DPB6not detectable1
PPP1R13LQ8WUF5not detectable1
PPP1R3GB7ZBB8not detectable1
PRKACAP17612not detectable1
PRKCAP17252not detectable1
PRKD2Q9BZL6not detectable1
PRLHRP49683not detectable1
PRR16Q569H4not detectable1
PSCDBPO60759not detectable1
PTH1RQ03431not detectable1
PTH2RP49190not detectable1
PTPN18Q99952not detectable1
PTPRGP23470not detectable1
PTPRZ1P23471not detectable1
PTTG2Q9NZH5not detectable1
RAB9AP51151not detectable1
RAMP3O60896not detectable1
RAPGEF2Q9Y4G8not detectable1
RAPGEF6Q8TEU7not detectable1
RASL11BQ9BPW5not detectable1
RCN1Q15293not detectable1
RCN2Q14257not detectable1
REELD1A0A1B0GV85not detectable1
RNF146Q9NTX7not detectable1
RPS6KA1Q15418(TPO)733not detectable1
RRBP1Q9P2E9not detectable1
RSBN1Q5VWQ0not detectable1
RSRC2Q7L4I2not detectable1
RTKNQ9BST9not detectable1
SAPCD1Q5SSQ6not detectable1
SBF1O95248not detectable1
SCN4AP35499not detectable1
SCN4BQ8IWT1not detectable1
SCN5AQ14524not detectable1
SCN8AQ9UQD0not detectable1
SDC2P34741not detectable1
SDC3O75056not detectable1
SDC4P31431not detectable1
SEMA4CQ9C0C4not detectable1
SEMA4FO95754not detectable1
SH2D3CQ8N5H7not detectable1
SHKBP1Q8TBC3not detectable1
SHROOM3Q8TF72not detectable1
SHROOM4Q9ULL8not detectable1
SIPA1Q96FS4not detectable1
SLC16A1P53985not detectable1
SLC16A3O15427not detectable1
SLC16A7O60669not detectable1
SLC17A1Q14916not detectable1
SLC1A1P43005not detectable1
SLC1A3P43003not detectable1
SLC1A4P43007not detectable1
SLC1A5Q15758not detectable1
SLC1A7O00341not detectable1
SLC22A11Q9NSA0not detectable1
SLC22A12Q96S37not detectable1
SLC22A3O75751not detectable1
SLC22A9Q8IVM8not detectable1
SLC23A1Q9UHI7not detectable1
SLC26A3P40879not detectable1
SLC2A3P11169not detectable1
SLC2A7Q6PXP3not detectable1
SLC34A1Q06495not detectable1
SLC45A4Q5BKX6not detectable1
SLC4A7Q9Y6M7not detectable1
SLC5A12Q1EHB4not detectable1
SLC9A3P48764not detectable1
SLCO1A2P46721not detectable1
SLCO1B1Q9Y6L6not detectable1
SLCO2B1O94956not detectable1
SMCHD1A6NHR9not detectable1
SORCS3Q9UPU3not detectable1
SSTR5P35346not detectable1
STK16O75716not detectable1
TAGAPQ8N103not detectable1
TANC1Q9C0D5not detectable1
TBC1D10AQ9BXI6not detectable1
TBPL1P62380not detectable1
TECPR2O15040not detectable1
TGFAP01135not detectable1
TIAM1Q13009not detectable1
TJP3O95049not detectable1
TMEM151BQ8IW70not detectable1
TMEM178BH3BS89not detectable1
TMEM225BP0DP42not detectable1
TMIGD1Q6UXZ0not detectable1
TNRC6AQ8NDV7not detectable1
TNRC6BQ9UPQ9not detectable1
TRAF2Q12933not detectable1
TRIM50Q86XT4not detectable1
TRIP6Q15654not detectable1
TRMT13Q9NUP7not detectable1
TRPC5Q9UL62not detectable1
TRPM1Q7Z4N2not detectable1
TRPV3Q8NET8not detectable1
TRPV6Q9H1D0not detectable1
TUBB4BP68371not detectable1
TYRO3Q06418not detectable1
TYRP1P17643not detectable1
U2AF2P26368not detectable1
UNC93AQ86WB7not detectable1
UQCRC2P22695not detectable1
USH1CQ9Y6N9not detectable1
VANGL1Q8TAA9not detectable1
XKR7Q5GH72not detectable1
ZNF599Q96NL3not detectable1
ZNF831Q5JPB2not detectable1
ZSCAN30Q86W11not detectable1





Page loaded in 0.635973 seconds.